MOTS-c (10mg)

Name: MOTS-c (10mg)
Brand: 4-Amino-Labs
SKU: MOTSC-10MG
Price: 50.00 USD
Availability: InStock

Inventory Status:
Available

Product Details

AvailabilityIn stock

SKUMOTSC-10MG

CategoryShort-Chain Amino Acids

Brand4-Amino-Labs

SKU MOTSC-10MG Category Short-Chain Amino Acids Tags mots c, motsc Brand: 4-Amino-Labs

$50.00

Price per mg

Total (10mg)$5.00/mg

Strict Regulatory Notice: This agent is synthesized strictly for laboratory-based research and analytical purposes. It is not intended for human or veterinary use, nor for medical, household, or cosmetic applications. Please review our Terms of Service thoroughly before finalizing your acquisition.

Concentration and Formulation

Contents10mg per vial

FormLyophilized powder

Available

For Research Use Only. Not for human or veterinary use.

Key Documents

SDS COA

SDS = Safety Data Sheet · COA = Certificate of Analysis

View All Documentation: Safety Data Sheets Certificates of Analysis

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Key Specifications

Parameter	Specification / Details
Primary Compound Name	MOTS-c (Mitochondrial Derived Peptide)
CAS Registry Number	1627580-64-6
Sequence / IUPAC	Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg
Molecular Formula	C101H152N28O22S2
Molar Mass / Weight	2174.6 g/mol
Physical Appearance	White lyophilized (freeze-dried) solid/powder
Solubility Profile	Highly soluble in Bacteriostatic Water and sterile water.
Tested Purity	≥98% via HPLC
Active Ingredient (Total)	10mg per vial
Dry / Powder Formulations	Lyophilized powder
Storage Guidelines	Lyophilized: Store at -20°C for long-term stability. Protect from light.Reconstituted: Must be refrigerated at 2°C to 8°C.
Estimated Shelf Life	24 months from manufacture date (lyophilized).
Terms of Application	For laboratory research purposes only. Not for human or veterinary use. Investigated as a mitochondrial-derived peptide evaluating AMPK activation, mitochondrial metabolic regulation, and skeletal muscle glucose homeostasis in cellular models.

Foundational Scientific Overview

MOTS-c (10mg) is a paramount subject within the field of mitochondrial bioenergetics and cellular metabolic homeostasis. Synthesized as a mitochondrial-derived peptide (MDP), it serves researchers examining the activation of the AMP-activated protein kinase (AMPK) pathway, glucose uptake modeling, and the prevention of diet-induced metabolic dysfunction in-vitro.

At 4-Amino-Labs, we provide this highly sensitive sequence in a stabilized lyophilized format to ensure experimental reproducibility. By maintaining rigorous measurement standards, we provide the consistency required for longitudinal data integrity.

The biochemical capacity of MOTS-c to act as a systemic metabolic regulator, targeting skeletal muscle to enhance insulin sensitivity and beta-oxidation, is a cornerstone of recent mitochondrial research. See: Lee, C., et al. (2015). "The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance." Cell Metabolism, 21(3), 443-454.

Analytical Composition and Purity

Purity≥98%via HPLC

FormulaC101H152N28O22S2

Physical StateWhite Lyophilized Solid

Investigational Pathways

AMPK Activation

Evaluating the compound’s role in phosphorylating AMP-activated protein kinase to drive cellular energy expenditure.

Glucose Metabolism

Observing the upregulation of glucose clearance and transport in isolated skeletal muscle models independently of insulin.

Mitochondrial Retrograde Signaling

Mapping the flux of communication from the mitochondria to the nuclear genome under metabolic stress.

Folate Cycle Modulation

Investigating the agent’s capacity to inhibit the folate cycle, triggering purine synthesis pathways related to metabolic regulation.

Laboratory Handling and Stability

Thermal Regulation

Store in a strictly controlled, refrigerated, and desiccated environment.

Photostability

Protect from direct UV exposure; storage in an opaque container is advised.

Contamination Control

Utilize sterilized instruments and work within a laminar flow hood where possible.

Compliance and Safety

This substance is provided exclusively for in-vitro laboratory research and pre-clinical developmental testing. 4-Amino-Labs does not condone or authorize the use of this product in any clinical setting or for personal consumption. Misuse of laboratory chemicals carries significant health risks. By purchasing, the researcher acknowledges the inherent risks and confirms they possess the necessary equipment and expertise to handle these materials safely.

Analytical Composition & Purity Standards

Chemical Formula: C101H152N28O22S2
Physical State: White Lyophilized Solid

Our MOTS-c undergoes a multifaceted verification process. Each batch is subjected to independent High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS) to ensure a purity threshold of ≥ 98%.

Investigational Pathways

Researchers utilizing MOTS-c typically focus on the following biochemical mechanisms:

AMPK Activation: Evaluating the compound’s role in phosphorylating AMP-activated protein kinase to drive cellular energy expenditure.
Glucose Metabolism: Observing the upregulation of glucose clearance and transport in isolated skeletal muscle models independently of insulin.
Mitochondrial Retrograde Signaling: Mapping the flux of communication from the mitochondria to the nuclear genome under metabolic stress.
Folate Cycle Modulation: Investigating the agent’s capacity to inhibit the folate cycle, triggering purine synthesis pathways related to metabolic regulation.

Laboratory Handling & Stability Protocol

To maintain the molecular integrity of MOTS-c, the following storage parameters are recommended:

Thermal Regulation: Store in a strictly controlled, refrigerated, and desiccated environment.
Photostability: Protect from direct UV exposure; storage in an opaque container is advised.
Contamination Control: Utilize sterilized instruments and work within a laminar flow hood where possible.