MK-777 (Acetamoren)

Inventory Status:

Available

Product Details
AvailabilityIn stock
SKUMK777
SKU MK777 Categories , Tags , Brand:

Price range: $65.00 through $95.00

Price per mg
30ml Vial (Liquid) (600mg)$0.108/mg
Tablets 50 Count (1,000mg)$0.095/mg

Strict Regulatory Notice: This agent is synthesized strictly for laboratory-based research and analytical purposes. It is not intended for human or veterinary use, nor for medical, household, or cosmetic applications. Please review our Terms of Service thoroughly before finalizing your acquisition.

Concentration and Formulation
Tablet Concentration50 Tablets (~20 mg/Tablet, laboratory reference use only)
Inactive IngredientsMicrocrystalline cellulose, Magnesium stearate, Dicalcium phosphate, Silicon dioxide,
Liquid Concentration And SolutionReference solution in PEG-400 / Ethanol
Nominal analytical concentration (~20 mg/mL, laboratory reference use only)
For Research Use Only. Not for human or veterinary use
Key Documents
SDS = Safety Data Sheet  ·  COA = Certificate of Analysis

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Key Specifications

ParameterSpecification / Details
Primary Compound NameAcetamoren (MK-777)
CAS Registry Number950841-87-9
IUPAC Designation(R)-2-Acetamido-N-(3-(benzyloxy)-1-(1-(methylsulfonyl)spiro[indoline-3,4'-piperidin]-1'-yl)-1-oxopropan-2-yl)-2-methylpropanamide
Synonyms / Trade NamesN-Acetyl Ibutamorelin, MK-777
PubChem CIDNovel Derivative (Not yet formally assigned in primary CID databases)
Molecular FormulaC₂₉H₃₈N₄O₆S
Molar Mass / Weight570.70 g/mol
Physical AppearanceWhite crystalline powder (raw) / Clear liquid (suspended)
Solubility ProfileSoluble in DMSO, PEG 400, and Ethanol. Insoluble in water.
Tested Purity≥98% via HPLC
Liquid Concentration20mg/mL in PEG-400 / Ethanol (600mg per 30mL vial)
Tablet Strength20mg per tablet (50 tablets, 1,000mg per bottle)
Alternative FormulationsIbutamoren (MK-677 - the non-acetylated parent compound)
Storage GuidelinesStore at room temperature (20°C to 25°C). Protect strictly from moisture, heat, and direct sunlight.
Estimated Shelf Life24 months from manufacture date.
Safety DocumentationStandard SDS available for Acetamoren
Terms of ApplicationFor laboratory research purposes only. Not for human or veterinary use. Investigated as a high-affinity, highly selective agonist of the ghrelin receptor (GHS-R1a) to evaluate mechanisms of growth hormone secretagogue activity and localized nutrient partitioning in in-vitro models.

Foundational Scientific Overview

Foundational Scientific Overview

MK777 is a specialized research compound closely related to the spiroindoline class of ghrelin mimetics. As an experimental growth hormone secretagogue analog, it serves researchers examining the highly targeted upstream regulation of the somatotropic axis and isolated IGF-1 transcription without the typical downstream modulation of peripheral lipid metabolism.

At 4-Amino-Labs, we provide this novel derivative in a highly purified format to ensure experimental reproducibility. By maintaining rigorous measurement standards, we provide the consistency required for longitudinal data integrity.

The ongoing synthesis of non-peptide secretagogues to isolate GH release from other neuroendocrine axes remains a critical area of molecular design. See: Patchett, A. A., et al. (1995). "Design and biological activities of L-163,191 (MK-0677): a potent, orally active growth hormone secretagogue." Proceedings of the National Academy of Sciences, 92(15), 7001-7005.

Analytical Composition and Purity

Purity≥98%via HPLC
FormulaC₂₉H₃₈N₄O₆S
Physical StateSupplied as 50-count tablets (20mg/tablet) and as a 20mg/mL solution in PEG-400 / Ethanol (raw material: fine crystalline solid)

Investigational Pathways

Receptor Specificity
Evaluating the compound’s selective binding kinetics to GHSR1a variations in pituitary cellular models.
Transcriptional Regulation
Observing the elevation of specific IGF-1 splice variants in isolated hepatic cells.
Neuroprotection
Mapping the flux of anti-apoptotic markers in induced-stress neuronal assays.

Laboratory Handling and Stability

Thermal Regulation
Store in a strictly controlled, desiccated environment at room temperature.
Photostability
Protect from direct UV exposure; storage in an opaque container is advised to prevent photodegradation.
Contamination Control
Use sterilized instruments and work within a laminar-flow hood, when possible, to maintain sample sterility.

Compliance and Safety

This substance is provided exclusively for in-vitro laboratory research and pre-clinical developmental testing. 4-Amino-Labs does not condone or authorize the use of this product in any clinical setting or for personal consumption. Misuse of laboratory chemicals carries significant health risks. By purchasing, the researcher acknowledges the inherent risks and confirms they possess the necessary equipment and expertise to handle these materials safely.

Analytical Composition & Purity Standards

  • Chemical Formula: C₂₉H₃₈N₄O₆S
  • Physical State: Supplied as 50-count tablets (20mg/tablet) and as a 20mg/mL solution in PEG-400 / Ethanol (raw material: fine crystalline solid)

Our MK777 undergoes a multifaceted verification process. Each batch is subjected to independent High-Performance Liquid Chromatography (HPLC) to ensure a purity threshold of ≥ 98%. This analytical rigor ensures the absence of unreacted synthetic precursors.

Investigational Pathways

Researchers utilizing MK777 typically focus on the following biochemical mechanisms:

  • Receptor Specificity: Evaluating the compound’s selective binding kinetics to GHSR1a variations in pituitary cellular models.
  • Transcriptional Regulation: Observing the elevation of specific IGF-1 splice variants in isolated hepatic cells.
  • Neuroprotection: Mapping the flux of anti-apoptotic markers in induced-stress neuronal assays.

Laboratory Handling & Stability Protocol

To maintain the molecular integrity of MK777, the following storage parameters are recommended:

  • Thermal Regulation: Store in a strictly controlled, desiccated environment at room temperature.
  • Photostability: Protect from direct UV exposure; storage in an opaque container is advised to prevent photodegradation.
  • Contamination Control: Use sterilized instruments and work within a laminar-flow hood, when possible, to maintain sample sterility.

Compliance & Safety Disclaimer

This substance is provided exclusively for in-vitro laboratory research and pre-clinical developmental testing. 4-Amino-Labs does not condone or authorize the use of this product in any clinical setting or for personal consumption. Misuse of laboratory chemicals carries significant health risks. By purchasing, the researcher acknowledges the inherent risks and confirms they possess the necessary equipment and expertise to handle these materials safely.

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MK-777 (Acetamoren)