GW0742 (Fitorine)
Inventory Status:
Available
$64.00
Strict Regulatory Notice: This agent is synthesized strictly for laboratory-based research and analytical purposes. It is not intended for human or veterinary use, nor for medical, household, or cosmetic applications. Please review our Terms of Service thoroughly before finalizing your acquisition.
15mg/mL solution (450mg/30mL)
Guaranteed Safe Checkout:
Key Specifications
| Parameter | Specification / Details |
|---|---|
| Primary Compound Name | GW0742 (PPARδ Agonist) |
| CAS Registry Number | 317318-84-6 |
| IUPAC Designation | 2-[4-[[[2-[3-fluoro-4-(trifluoromethyl)phenyl]-4-methyl-1,3-thiazol-5-yl]methyl]sulfanyl]-2-methylphenoxy]acetic acid |
| Synonyms / Trade Names | GW610742, Fitorine, Super Cardarine |
| PubChem CID | 9845701 |
| Molecular Formula | C₂₁H₁₇F₄NO₃S₂ |
| Molar Mass / Weight | 471.5 g/mol |
| Physical Appearance | Clear or slightly tinted liquid |
| Solubility Profile | Soluble in DMSO, Ethanol, and Propylene Glycol/PEG 400. Insoluble in water. |
| Tested Purity | ≥99% via HPLC |
| Active Ingredient (Total) | 600mg per 30mL vial |
| Dry / Powder Formulations | N/A (Liquid suspension) |
| Liquid / Solution Concentrations | 20mg/mL in a PEG 400 / Ethanol carrier |
| Alternative Formulations | GW501516 (Cardarine - a closely related PPARδ agonist) |
| Storage Guidelines | Store at room temperature (20°C to 25°C). Protect from moisture, heat, and direct sunlight. |
| Estimated Shelf Life | 24 months from manufacture date. |
| Safety Documentation | Standard SDS available for GW0742 |
| Terms of Application | For laboratory research purposes only. Not for human or veterinary use. |
Foundational Scientific Overview
GW0742 (Fitorine) is a prominent subject within the field of metabolic transcription and lipid homeostasis. Synthesized as a highly selective peroxisome proliferator-activated receptor delta (PPARδ) agonist, it serves researchers examining the genomic reprogramming of skeletal muscle, fatty acid oxidation, and the mitigation of ischemic-reperfusion injury.
At 4 Amino Labs, we provide this non-steroidal compound in a highly pure format to ensure experimental reproducibility. By maintaining rigorous measurement standards, we provide the consistency required for longitudinal data integrity.
Scientific Literature Reference: The interaction between PPARδ activation and the profound alteration of systemic lipid metabolism and cytoprotection is deeply documented. See: Zuo, X., et al. (2012). “Activation of PPAR delta protects the mouse heart from ischemia/reperfusion injury.” FEBS Letters, 586(13), 1845-1849.
Analytical Composition & Purity Standards
- Chemical Formula: C21H17F4NO3S2
- Physical State: Fine White to Pale-Yellow Powder
Our GW0742 undergoes a multifaceted verification process. Each batch is subjected to independent High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS) to ensure a purity threshold of ≥ 99%.
Investigational Pathways
Researchers utilizing GW0742 typically focus on the following biochemical mechanisms:
- Transcriptional Regulation: Evaluating the compound’s binding to PPARδ and the subsequent recruitment of co-activators to drive gene expression.
- Lipid Catabolism: Observing the upregulation of genes involved in cellular fatty acid transport and mitochondrial beta-oxidation.
- Anti-Inflammatory Modeling: Mapping the flux of cytokine suppression in isolated macrophage and endothelial cell cultures.
- Cardiac Cytoprotection: Investigating the agent’s capacity to preserve myocardial cell viability during induced hypoxic states.
Laboratory Handling & Stability Protocol
To maintain the molecular integrity of GW0742, the following storage parameters are recommended:
- Thermal Regulation: Store in a strictly controlled, desiccated environment at room temperature.
- Photostability: Protect from direct UV exposure; storage in an opaque container or dark cabinet is advised to prevent photodegradation.
- Contamination Control: Use sterilized instruments and work within a laminar-flow hood, when possible, to maintain sample sterility.
Compliance & Safety Disclaimer
This substance is provided exclusively for in-vitro laboratory research and pre-clinical developmental testing. 4 Amino Lab does not condone or authorize the use of this product in any clinical setting or for personal consumption. Misuse of laboratory chemicals carries significant health risks. By purchasing, the researcher acknowledges the inherent risks and confirms they possess the necessary equipment and expertise to handle these materials safely.
