GW0742 (Fitorine)

Inventory Status:
Available

Product Details

AvailabilityIn stock

SKUGW0742

CategoryReceptor Modulators

Brand4-Amino-Labs

SKU GW0742 Category Receptor Modulators Tags fitorine, gw-0742 Brand: 4-Amino-Labs

$64.00

Price per mg

30ml Vial (Liquid) (450mg)$0.142/mg

Strict Regulatory Notice: This agent is synthesized strictly for laboratory-based research and analytical purposes. It is not intended for human or veterinary use, nor for medical, household, or cosmetic applications. Please review our Terms of Service thoroughly before finalizing your acquisition.

Concentration and Formulation

Contents450mg per 30mL vial

Concentration15mg/mL in a PEG 400 / Ethanol carrier

Size

30ml Vial (Liquid)

Clear

For Research Use Only. Not for human or veterinary use.

Key Documents

SDS COA

SDS = Safety Data Sheet · COA = Certificate of Analysis

View All Documentation: Safety Data Sheets Certificates of Analysis

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Key Specifications

Parameter	Specification / Details
Primary Compound Name	GW0742 (PPARδ Agonist)
CAS Registry Number	317318-84-6
IUPAC Designation	2-[4-[[[2-[3-fluoro-4-(trifluoromethyl)phenyl]-4-methyl-1,3-thiazol-5-yl]methyl]sulfanyl]-2-methylphenoxy]acetic acid
Synonyms / Trade Names	GW610742, Fitorine, Super Cardarine
PubChem CID	9845701
Molecular Formula	C₂₁H₁₇F₄NO₃S₂
Molar Mass / Weight	471.5 g/mol
Physical Appearance	Clear or slightly tinted liquid
Solubility Profile	Soluble in DMSO, Ethanol, and Propylene Glycol/PEG 400. Insoluble in water.
Tested Purity	≥99% via HPLC
Active Ingredient (Total)	450mg per 30mL vial
Dry / Powder Formulations	N/A (Liquid suspension)
Liquid / Solution Concentrations	15mg/mL in a PEG 400 / Ethanol carrier
Alternative Formulations	GW501516 (Cardarine - a closely related PPARδ agonist)
Storage Guidelines	Store at room temperature (20°C to 25°C). Protect from moisture, heat, and direct sunlight.
Estimated Shelf Life	24 months from manufacture date.
Safety Documentation	Standard SDS available for GW0742
Terms of Application	For laboratory research purposes only. Not for human or veterinary use.

Foundational Scientific Overview

GW0742 (Fitorine) is a prominent subject within the field of metabolic transcription and lipid homeostasis. Synthesized as a highly selective peroxisome proliferator-activated receptor delta (PPARδ) agonist, it serves researchers examining the genomic reprogramming of skeletal muscle, fatty acid oxidation, and the mitigation of ischemic-reperfusion injury.

At 4-Amino-Labs, we provide this non-steroidal compound in a highly pure format to ensure experimental reproducibility. By maintaining rigorous measurement standards, we provide the consistency required for longitudinal data integrity.

The interaction between PPARδ activation and the profound alteration of systemic lipid metabolism and cytoprotection is deeply documented. See: Zuo, X., et al. (2012). "Activation of PPAR delta protects the mouse heart from ischemia/reperfusion injury." FEBS Letters, 586(13), 1845-1849.

Analytical Composition and Purity

Purity≥99%via HPLC

FormulaC21H17F4NO3S2

Physical StateClear or slightly tinted solution, 15mg/mL in a PEG 400 / Ethanol carrier (raw material: fine white to pale-yellow powder)

Investigational Pathways

Transcriptional Regulation

Evaluating the compound’s binding to PPARδ and the subsequent recruitment of co-activators to drive gene expression.

Lipid Catabolism

Observing the upregulation of genes involved in cellular fatty acid transport and mitochondrial beta-oxidation.

Anti-Inflammatory Modeling

Mapping the flux of cytokine suppression in isolated macrophage and endothelial cell cultures.

Cardiac Cytoprotection

Investigating the agent’s capacity to preserve myocardial cell viability during induced hypoxic states.

Laboratory Handling and Stability

Thermal Regulation

Store in a strictly controlled, desiccated environment at room temperature.

Photostability

Protect from direct UV exposure; storage in an opaque container or dark cabinet is advised to prevent photodegradation.

Contamination Control

Use sterilized instruments and work within a laminar-flow hood, when possible, to maintain sample sterility.

Compliance and Safety

This substance is provided exclusively for in-vitro laboratory research and pre-clinical developmental testing. 4-Amino-Labs does not condone or authorize the use of this product in any clinical setting or for personal consumption. Misuse of laboratory chemicals carries significant health risks. By purchasing, the researcher acknowledges the inherent risks and confirms they possess the necessary equipment and expertise to handle these materials safely.

Analytical Composition & Purity Standards

Chemical Formula: C21H17F4NO3S2
Physical State: Clear or slightly tinted solution, 15mg/mL in a PEG 400 / Ethanol carrier (raw material: fine white to pale-yellow powder)

Our GW0742 undergoes a multifaceted verification process. Each batch is subjected to independent High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS) to ensure a purity threshold of ≥ 99%.

Investigational Pathways

Researchers utilizing GW0742 typically focus on the following biochemical mechanisms:

Transcriptional Regulation: Evaluating the compound’s binding to PPARδ and the subsequent recruitment of co-activators to drive gene expression.
Lipid Catabolism: Observing the upregulation of genes involved in cellular fatty acid transport and mitochondrial beta-oxidation.
Anti-Inflammatory Modeling: Mapping the flux of cytokine suppression in isolated macrophage and endothelial cell cultures.
Cardiac Cytoprotection: Investigating the agent’s capacity to preserve myocardial cell viability during induced hypoxic states.

Laboratory Handling & Stability Protocol

To maintain the molecular integrity of GW0742, the following storage parameters are recommended:

Thermal Regulation: Store in a strictly controlled, desiccated environment at room temperature.
Photostability: Protect from direct UV exposure; storage in an opaque container or dark cabinet is advised to prevent photodegradation.
Contamination Control: Use sterilized instruments and work within a laminar-flow hood, when possible, to maintain sample sterility.