TB-500
Inventory Status:
Availability: Available
Price range: $52.00 through $84.00
Strict Regulatory Notice: This agent is synthesized strictly for laboratory-based research and analytical purposes. It is not intended for human or veterinary use, nor for medical, household, or cosmetic applications. Please review our Terms of Service thoroughly before finalizing your acquisition.
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Key Specifications
| Parameter | Specification / Details |
|---|---|
| Primary Compound Name | Thymosin Beta-4 (TB-500) |
| CAS Registry Number | 77591-33-4 |
| Sequence / IUPAC Equivalent | Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser |
| Synonyms / Trade Names | Tβ4, Thymosin β4, TB500 |
| PubChem CID | 16132341 |
| Molecular Formula | C₂₁₂H₃₅₀N₅₆O₇₈S |
| Molar Mass / Weight | 4963.44 g/mol |
| Physical Appearance | White lyophilized (freeze-dried) solid/powder |
| Solubility Profile | Readily soluble in water and bacteriostatic saline |
| Tested Purity | ≥99% via HPLC |
| Active Ingredient (Total) | [e.g., 2mg, 5mg, or 10mg per vial] |
| Dry / Powder Formulations | Lyophilized cake/powder under vacuum |
| Liquid / Solution Concentrations | Requires reconstitution with Bacteriostatic Water |
| Alternative Formulations | Frequently stacked or blended with BPC-157 |
| Storage Guidelines | Lyophilized: Store at -20°C for long-term stability. Reconstituted: Must be refrigerated at 2°C to 8°C (36°F to 46°F). |
| Estimated Shelf Life | 24+ months (lyophilized). 14 to 21 days (reconstituted and refrigerated). |
| Safety Documentation | Standard SDS available for Thymosin Beta-4 Peptide |
| Terms of Application | For laboratory research purposes only. Not for human or veterinary use. |
Foundational Scientific Overview
TB-500 (5mg) is a prominent subject within the field of cellular motility, actin sequestration, and angiogenesis research. Originally synthesized as a synthetic fractional active domain of the naturally occurring protein Thymosin Beta-4, it has become a staple for researchers examining endothelial cell differentiation and the structural remodeling of damaged tissues.
At 4 Amino Labs, we provide this compound in a stabilized lyophilized powder to ensure experimental reproducibility. By maintaining rigorous measurement standards, we provide the consistency required for longitudinal data integrity. This compound is frequently cited in peer-reviewed literature due to its well-documented low molecular weight, which allows for exceptional tissue penetrability, and its primary binding affinity for G-actin monomers.
Analytical Composition & Purity Standards
- Chemical Formula: C212H350N56O78S
- Physical State: White Lyophilized Solid
Our TB-500 (5mg) undergoes a multifaceted verification process. Each batch is subjected to independent High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS) to ensure a purity threshold of ≥ 99%. This analytical rigor ensures the absence of residual solvents, heavy metals, or cross-contaminants, providing a stable baseline for your in-vitro or pre-clinical models.
Investigational Pathways
Researchers utilizing TB-500 (5mg) typically focus on the following biochemical mechanisms:
- Actin Regulation: Evaluating the compound’s ability to sequester G-actin and prevent its polymerization into F-actin, maintaining cellular fluidity.
- Angiogenesis: Observing the formation of new blood vessels from pre-existing microvascular networks in in-vitro assays.
- Anti-fibrotic Action: Mapping the flux of collagen deposition and the inhibition of excessive scar tissue formation in cellular injury models.
- Myocyte Survival: Investigating the agent’s cytoprotective role against induced ischemia or hypoxic stress in cardiac or skeletal muscle cells.
Laboratory Handling & Stability Protocol
To maintain the molecular integrity of TB-500 (5mg), the following storage parameters are recommended:
- Thermal Regulation: Store in a controlled, cool, and desiccated environment. Reconstituted peptides must be refrigerated.
- Photostability: Protect from direct UV exposure; storage in an opaque container or dark cabinet is advised to prevent photodegradation.
- Hygroscopic Prevention: Ensure the seal is hermetic after every withdrawal to prevent moisture absorption and clumping.
- Contamination Control: Use sterilized instruments and work within a laminar-flow hood, when possible, to maintain sample sterility.
Compliance & Safety Disclaimer
This substance is provided exclusively for in-vitro laboratory research and pre-clinical developmental testing. 4 Amino Lab does not condone or authorize the use of this product in any clinical setting or for personal consumption. Misuse of laboratory chemicals carries significant health risks. By purchasing, the researcher acknowledges the inherent risks and confirms they possess the necessary equipment and expertise to handle these materials safely.
