SR9009 (Stenabolic)

Inventory Status:

Available

Product Details
AvailabilityIn stock
SKUSR9009
SKU SR9009 Category Tags , Brand:

$65.00

Price per mg
30ml Vial (Liquid) (900mg)$0.072/mg

Strict Regulatory Notice: This agent is synthesized strictly for laboratory-based research and analytical purposes. It is not intended for human or veterinary use, nor for medical, household, or cosmetic applications. Please review our Terms of Service thoroughly before finalizing your acquisition.

Concentration and Formulation
Contents900mg per 30mL vial
Concentration30mg/mL in a PEG 400 / Ethanol carrier
For Research Use Only. Not for human or veterinary use.
Key Documents
SDS = Safety Data Sheet  ·  COA = Certificate of Analysis

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Key Specifications

ParameterSpecification / Details
Primary Compound NameSR9009 (REV-ERB Agonist)
CAS Registry Number1379686-30-2
IUPAC Designationethyl 3-[[[(4-chlorophenyl)methyl][(5-nitrothiophen-2-yl)methyl]amino]methyl]pyrrolidine-1-carboxylate
Synonyms / Trade NamesStenabolic, SR-9009
PubChem CID71765050
Molecular FormulaC₂₀H₂₄ClN₃O₄S
Molar Mass / Weight437.94 g/mol
Physical AppearanceWhite to off-white crystalline powder (raw) / Clear or slightly tinted liquid (suspended)
Solubility ProfileSoluble in DMSO, Ethanol, and Propylene Glycol/PEG 400. Insoluble in water.
Tested Purity≥98% via HPLC
Active Ingredient (Total)900mg per 30mL vial
Dry / Powder FormulationsN/A (Liquid suspension)
Liquid / Solution Concentrations30mg/mL in a PEG 400 / Ethanol carrier
Alternative FormulationsSR9011 (a closely related REV-ERB agonist)
Storage GuidelinesStore at room temperature (20°C to 25°C). Protect strictly from moisture, heat, and direct sunlight.
Estimated Shelf Life24 months from manufacture date.
Safety DocumentationStandard SDS available for SR9009
Terms of ApplicationFor laboratory research purposes only. Not for human or veterinary use. Investigated for its role as a REV-ERBα and REV-ERBβ agonist to study circadian rhythm regulation, lipid metabolism, and mitochondrial biogenesis in in-vitro models.

Foundational Scientific Overview

Foundational Scientific Overview

SR9009 (Stenabolic) is a prominent subject within the field of chronobiology, mitochondrial biogenesis, and lipid metabolism. Synthesized as a highly specific agonist for the Rev-ErbAɑ and Rev-Erbβ nuclear receptors, it has become a staple for researchers examining the genomic synchronization of the circadian rhythm with cellular energy expenditure.

At 4-Amino-Labs, we provide this non-hormonal compound in a highly purified format to ensure experimental reproducibility. By maintaining rigorous measurement standards, we provide the consistency required for longitudinal data integrity.

The interaction between synthetic Rev-Erb agonists and the profound alteration of circadian behavior, cholesterol metabolism, and exercise endurance is deeply documented. See: Solt, L. A., et al. (2012). "Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists." Nature, 485(7396), 62-68.

Analytical Composition and Purity

Purity≥98%via HPLC
FormulaC20H24ClN3O4S
Physical StateClear or slightly tinted solution, 30mg/mL in a PEG 400 / Ethanol carrier (raw material: fine white to off-white crystalline powder)

Investigational Pathways

Rev-ErbA Activation
Evaluating the compound’s influence on repressing specific metabolic genes involved in lipid and glucose storage.
Circadian Synchronization
Observing the modulation of core clock genes (e.g., BMAL1) in disrupted or asynchronous cellular models.
Mitochondrial Density
Mapping the profound increase in mitochondrial genesis and macrophage cholesterol efflux in-vitro.
Lipogenesis Inhibition
Investigating the reduction of de novo lipogenesis in isolated hepatic cells.

Laboratory Handling and Stability

Thermal Regulation
Store in a strictly controlled, desiccated environment at room temperature.
Photostability
Protect from direct UV exposure; storage in an opaque container is advised.
Contamination Control
Use sterilized instruments and work within a laminar-flow hood, when possible, to maintain sample sterility.

Compliance and Safety

This substance is provided exclusively for in-vitro laboratory research and pre-clinical developmental testing. 4-Amino-Labs does not condone or authorize the use of this product in any clinical setting or for personal consumption. Misuse of laboratory chemicals carries significant health risks. By purchasing, the researcher acknowledges the inherent risks and confirms they possess the necessary equipment and expertise to handle these materials safely.

Analytical Composition & Purity Standards

  • Chemical Formula: C20H24ClN3O4S
  • Physical State: Clear or slightly tinted solution, 30mg/mL in a PEG 400 / Ethanol carrier (raw material: fine white to off-white crystalline powder)

Our SR9009 undergoes a multifaceted verification process. Each batch is subjected to independent High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS) to ensure a purity threshold of ≥ 98%.

Investigational Pathways

Researchers utilizing SR9009 typically focus on the following biochemical mechanisms:

  • Rev-ErbA Activation: Evaluating the compound’s influence on repressing specific metabolic genes involved in lipid and glucose storage.
  • Circadian Synchronization: Observing the modulation of core clock genes (e.g., BMAL1) in disrupted or asynchronous cellular models.
  • Mitochondrial Density: Mapping the profound increase in mitochondrial genesis and macrophage cholesterol efflux in-vitro.
  • Lipogenesis Inhibition: Investigating the reduction of de novo lipogenesis in isolated hepatic cells.

Laboratory Handling & Stability Protocol

To maintain the molecular integrity of SR9009, the following storage parameters are recommended:

  • Thermal Regulation: Store in a strictly controlled, desiccated environment at room temperature.
  • Photostability: Protect from direct UV exposure; storage in an opaque container is advised.
  • Contamination Control: Use sterilized instruments and work within a laminar-flow hood, when possible, to maintain sample sterility.

Compliance & Safety Disclaimer

This substance is provided exclusively for in-vitro laboratory research and pre-clinical developmental testing. 4-Amino-Labs does not condone or authorize the use of this product in any clinical setting or for personal consumption. Misuse of laboratory chemicals carries significant health risks. By purchasing, the researcher acknowledges the inherent risks and confirms they possess the necessary equipment and expertise to handle these materials safely.

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SR9009 (Stenabolic)