Sermorelin (5mg)
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Availability: Available
$45.00
Strict Regulatory Notice: This agent is synthesized strictly for laboratory-based research and analytical purposes. It is not intended for human or veterinary use, nor for medical, household, or cosmetic applications. Please review our Terms of Service thoroughly before finalizing your acquisition.
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Key Specifications
| Category | Parameter | Specification / Details |
|---|---|---|
| Identification & Nomenclature | Primary Compound Name | Sermorelin (GHRH 1-29) |
| CAS Registry Number | 86168-78-7 | |
| Sequence / IUPAC | Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-NH2 | |
| Chemical & Physical Properties | Molecular Formula | C149H246N44O42S |
| Molar Mass / Weight | 3357.9 g/mol | |
| Physical Appearance | White lyophilized (freeze-dried) solid/powder | |
| Solubility Profile | Highly soluble in Bacteriostatic Water and sterile water. | |
| Product Specifications | Tested Purity | ≥98% via HPLC |
| Active Ingredient (Total) | 5mg per vial | |
| Dry / Powder Formulations | Lyophilized powder | |
| Handling & Logistics | Storage Guidelines | Lyophilized: Store at -20°C for long-term stability. Protect from light.Reconstituted: Must be refrigerated at 2°C to 8°C. |
| Estimated Shelf Life | 24 months from manufacture date (lyophilized). | |
| Terms of Application | For laboratory research purposes only. Not for human or veterinary use. Investigated as an endogenous Growth Hormone-Releasing Hormone (GHRH) fragment to evaluate the natural stimulation and preservation of the pituitary GH axis in in-vitro and cellular models. |
Foundational Scientific Overview
Sermorelin (5mg) is a fundamental subject within the field of neuroendocrinology and somatotropic axis modeling. Synthesized as an exact 29-amino acid structural fragment of naturally occurring Growth Hormone-Releasing Hormone (GHRH 1-29), it has become a staple for researchers examining the physiological induction of pituitary GH release, diagnostic pituitary functionality, and deep sleep architecture.
At 4 Amino Labs, we provide this foundational sequence in a highly pure format to ensure experimental reproducibility.
Scientific Literature Reference: The biochemical documentation of the 1-29 sequence representing the fully functional biological core of endogenous GHRH is a cornerstone of neuroendocrinology. See: Walker, R. F., et al. (1990). “Stimulation of pituitary growth hormone release in telemetrically monitored rats by a synthetic somatocrinin analog (sermorelin).” Neuroendocrinology, 51(4), 434-441.
Analytical Composition & Purity Standards
- Chemical Formula: C149H246N44O42S
- Physical State: White Lyophilized Solid
Our Sermorelin undergoes a multifaceted verification process via independent High-Performance Liquid Chromatography (HPLC) to ensure a purity threshold of ≧ 99%.
Investigational Pathways
Researchers utilizing Sermorelin typically focus on the following biochemical mechanisms:
- GHRH Receptor Agonism: Evaluating the compound’s direct interaction with the anterior pituitary, leading to cAMP accumulation.
- Endogenous Feedback Preservation: Observing the capacity of somatostatin to naturally down-regulate GH release initiated by Sermorelin, maintaining normal physiological feedback loops.
- Cellular Anabolism: Mapping the downstream flux of localized IGF-1 transcription in isolated muscle and hepatic cells.
Laboratory Handling & Stability Protocol
To maintain the molecular integrity of Sermorelin, the following storage parameters are recommended:
- Thermal Regulation: Extremely heat-sensitive once reconstituted. Store unmixed powder at -20°C for long-term preservation.
- Photostability: Protect from direct UV exposure; storage in an opaque container is advised.
- Contamination Control: Utilize sterilized instruments and work within a laminar flow hood where possible.
Compliance & Safety Disclaimer
This substance is provided exclusively for in-vitro laboratory research and pre-clinical developmental testing. 4 Amino Lab does not condone or authorize the use of this product in any clinical setting or for personal consumption. Misuse of laboratory chemicals carries significant health risks. By purchasing, the researcher acknowledges the inherent risks and confirms they possess the necessary equipment and expertise to handle these materials safely.
