MIC + B12 30ml

Inventory Status:

Available

Product Details
AvailabilityIn stock
SKUMICB12-30ML
SKU MICB12-30ML Category Tags , , Brand:

$63.00

Price per mg
Total actives (3,030mg)$0.021/mg
Inositol 1,500mg · Methionine 750mg · Choline 750mg · B12 30mg

Strict Regulatory Notice: This agent is synthesized strictly for laboratory-based research and analytical purposes. It is not intended for human or veterinary use, nor for medical, household, or cosmetic applications. Please review our Terms of Service thoroughly before finalizing your acquisition.

Concentration and Formulation
Active Ingredients (per mL)Methylcobalamin (B12) — 1000 mcg
Methionine — 25 mg
Inositol — 50 mg
Choline — 25 mg
Inactive IngredientsBenzyl Alcohol 1.5% v/v as preservative, Ammonium Sulfate 0.1%.

Available

For Research Use Only. Not for human or veterinary use.
Key Documents
SDS = Safety Data Sheet  ·  COA = Certificate of Analysis

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Key Specifications

ParameterSpecification / Details
Primary Compound NameMIC + B12 (Methionine, Inositol, Choline, Methylcobalamin)
Component 1L-Methionine (Essential Sulfur-containing Amino Acid)
Component 2Inositol (Vitamin-like Cyclitol)
Component 3Choline Chloride (Essential Nutrient/Phospholipid Precursor)
Component 4Methylcobalamin (Vitamin B12)
Physical AppearanceClear, vibrant red aqueous solution (due to B12)
Solubility ProfileFully miscible aqueous solution
Concentration (per mL)Methionine: 25mg / Inositol: 50mg / Choline: 25mg / Methylcobalamin (B12): 1mg (1000mcg)
Total Package Yield750mg Methionine / 1500mg Inositol / 750mg Choline / 30mg Methylcobalamin per 30mL
Inactive IngredientsBenzyl Alcohol 1.5% v/v (preservative), Ammonium Sulfate 0.1%, Sterile Deionized Water
Storage GuidelinesStore at 20°C to 25°C. Photosensitive: Protect strictly from direct light to prevent B12 degradation.
Estimated Shelf Life24 months from manufacture date.
Safety DocumentationStandard SDS available for MIC + B12 solutions
Terms of ApplicationFor laboratory research purposes only. Not for human or veterinary use. Investigated for its role in one-carbon metabolism and the methionine cycle, including S-adenosylmethionine (SAMe) synthesis, phosphatidylcholine production and mitochondrial energy flux in in-vitro hepatocyte models.

Foundational Scientific Overview

Foundational Scientific Overview

MIC + B12 (30ml) is a prominent subject within the field of methyl-donor biochemistry and phospholipid metabolism. Formulated as a precise blend of Methionine, Inositol, Choline, and Methylcobalamin (B12), it is studied by researchers examining cellular methylation, phosphatidylcholine synthesis, and transsulfuration cascades.

At 4-Amino-Labs, we provide this compound in a highly stable aqueous format to ensure experimental reproducibility. By maintaining rigorous measurement standards, we provide the consistency required for longitudinal data integrity.

The roles of choline and methionine in phospholipid synthesis and cellular methylation are well established. See: Zeisel, S. H. (2006). "Choline: critical role during fetal development and dietary requirements in adults." Annual Review of Nutrition, 26, 229-250. and Finkelstein, J. D. (1990). "Methionine metabolism in mammals." The Journal of Nutritional Biochemistry, 1(5), 228-237.

Analytical Composition and Purity

FormulaMulti-Component Methyl-Donor Blend (C5H11NO2S, C6H12O6, C5H14NO, C63H91CoN13O14P)
Physical StateRed Aqueous Solution

Investigational Pathways

Lipoprotein Assembly
Evaluating the role of choline-derived phosphatidylcholine in very-low-density lipoprotein (VLDL) assembly in isolated hepatocyte models.
Methylation Cycles
Observing the conversion of homocysteine to methionine and the generation of S-adenosylmethionine (SAMe).
Cellular Membrane Integrity
Mapping the flux of phosphatidylcholine synthesis mediated by the inositol and choline constituents.
Mitochondrial Bioenergetics
Investigating the role of B12 as a coenzyme in the methylmalonyl-CoA mutase pathway.

Laboratory Handling and Stability

Thermal Regulation
Store in a controlled room-temperature environment (20°C to 25°C). Avoid excessive heat and do not freeze.
Photostability
The B12 constituent is highly photosensitive. Storage in an opaque container or dark cabinet is strictly advised to prevent cleavage of the cobalt bonds.
Contamination Control
Use sterilized instruments and work within a laminar-flow hood, when possible, to maintain sample sterility.

Compliance and Safety

This substance is provided exclusively for in-vitro laboratory research and pre-clinical developmental testing. 4-Amino-Labs does not condone or authorize the use of this product in any clinical setting or for personal consumption. Misuse of laboratory chemicals carries significant health risks. By purchasing, the researcher acknowledges the inherent risks and confirms they possess the necessary equipment and expertise to handle these materials safely.

Analytical Composition & Purity Standards

  • Chemical Formula: Multi-Component Methyl-Donor Blend (C5H11NO2S, C6H12O6, C5H14NO, C63H91CoN13O14P)
  • Physical State: Red Aqueous Solution

Our MIC + B12 undergoes a multifaceted verification process. Each batch is subjected to independent High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS) to verify the precise stoichiometric ratio of the blend, ensuring a collective purity threshold of ≥ 99%.

Investigational Pathways

Researchers utilizing MIC + B12 typically focus on the following biochemical mechanisms:

  • Lipoprotein Assembly: Evaluating the role of choline-derived phosphatidylcholine in very-low-density lipoprotein (VLDL) assembly in isolated hepatocyte models.
  • Methylation Cycles: Observing the conversion of homocysteine to methionine and the generation of S-adenosylmethionine (SAMe).
  • Cellular Membrane Integrity: Mapping the flux of phosphatidylcholine synthesis mediated by the inositol and choline constituents.
  • Mitochondrial Bioenergetics: Investigating the role of B12 as a coenzyme in the methylmalonyl-CoA mutase pathway.

Laboratory Handling & Stability Protocol

To maintain the molecular integrity of MIC + B12, the following storage parameters are recommended:

  • Thermal Regulation: Store in a controlled room-temperature environment (20°C to 25°C). Avoid excessive heat and do not freeze.
  • Photostability: The B12 constituent is highly photosensitive. Storage in an opaque container or dark cabinet is strictly advised to prevent cleavage of the cobalt bonds.
  • Contamination Control: Use sterilized instruments and work within a laminar-flow hood, when possible, to maintain sample sterility.

Compliance & Safety Disclaimer

This substance is provided exclusively for in-vitro laboratory research and pre-clinical developmental testing. 4-Amino-Labs does not condone or authorize the use of this product in any clinical setting or for personal consumption. Misuse of laboratory chemicals carries significant health risks. By purchasing, the researcher acknowledges the inherent risks and confirms they possess the necessary equipment and expertise to handle these materials safely.

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MIC + B12 30ml