LGD-3303
Inventory Status:
Available
$84.00
Strict Regulatory Notice: This agent is synthesized strictly for laboratory-based research and analytical purposes. It is not intended for human or veterinary use, nor for medical, household, or cosmetic applications. Please review our Terms of Service thoroughly before finalizing your acquisition.
20mg/mL solution (600mg/30mL)
20mg/mL Oil (400mg/20mL)
Guaranteed Safe Checkout:
Key Specifications
| Parameter | Specification / Details |
|---|---|
| Primary Compound Name | LGD-3303 (Selective Androgen Receptor Modulator) |
| CAS Registry Number | 917891-35-1 |
| IUPAC Designation | 9-chloro-2-ethyl-1-methyl-3-(2,2,2-trifluoroethyl)-6H-pyrrolo[3,2-f]quinolin-7-one |
| Synonyms / Trade Names | LGD3303 |
| PubChem CID | 25195253 |
| Molecular Formula | C₁₆H₁₄ClF₃N₂O |
| Molar Mass / Weight | 342.74 g/mol |
| Physical Appearance | Clear or slightly tinted liquid |
| Solubility Profile | Soluble in DMSO, Ethanol, and Propylene Glycol/PEG 400. Insoluble in water. |
| Tested Purity | ≥99% via HPLC |
| Active Ingredient (Total) | 300mg per 30mL vial |
| Dry / Powder Formulations | N/A (Liquid suspension) |
| Liquid / Solution Concentrations | 10mg/mL in a PEG 400 / Ethanol carrier |
| Alternative Formulations | LGD-4033 (Ligandrol - a closely related, more common SARM) |
| Storage Guidelines | Store at room temperature (20°C to 25°C). Protect from moisture, heat, and direct sunlight. |
| Estimated Shelf Life | 24 months from manufacture date. |
| Safety Documentation | Standard SDS available for LGD-3303 |
| Terms of Application | For laboratory research purposes only. Not for human or veterinary use. |
Foundational Scientific Overview
LGD3303 is a prominent subject within the field of musculoskeletal research and targeted anabolism. Synthesized as a highly potent, non-steroidal Selective Androgen Receptor Modulator (SARM), it serves researchers examining the tissue-selective binding of the androgen receptor (AR) designed to act as a full agonist in muscle and bone tissues, contrasting with the partial agonism seen in older SARM generations.
At 4 Amino Labs, we provide this compound in a highly pure format to ensure experimental reproducibility. By maintaining rigorous measurement standards, we provide the consistency required for longitudinal data integrity.
Scientific Literature Reference: The biochemical capacity of this specific structural class to induce profound osteoanabolic activity and prevent bone loss in pre-clinical models is highly documented. See: Vajda, E. G., et al. (2009). “Pharmacokinetics and efficacy of a novel, nonsteroidal, orally active selective androgen receptor modulator (SARM) in a rat model of osteoporosis.” Bone, 44(1), 114-122.
Analytical Composition & Purity Standards
- Chemical Formula: C16H14ClF3N2O
- Physical State: Fine Crystalline Solid
Our LGD3303 undergoes a multifaceted verification process. Each batch is subjected to independent High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS) to ensure a purity threshold of ≥ 99%. This analytical rigor ensures the absolute absence of steroidal cross-contaminants.
Investigational Pathways
Researchers utilizing LGD3303 typically focus on the following biochemical mechanisms:
- Full AR Agonism: Evaluating the compound’s high-affinity binding kinetics and complete transcriptional activation at the androgen receptor within isolated myocyte cultures.
- Bone Mineralization: Mapping the flux of bone mineral density markers and osteoblast proliferation in musculoskeletal assays.
- Nitrogen Retention: Observing the reduction of protein degradation rates in catabolic cellular environments.
- Tissue Sparing Models: Investigating the minimal transcriptional activity in isolated prostate cellular models compared to standard steroidal controls.
Laboratory Handling & Stability Protocol
To maintain the molecular integrity of LGD3303, the following storage parameters are recommended:
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- Thermal Regulation: Store in a strictly controlled, desiccated environment at room temperature.
- Photostability: Protect from direct UV exposure; storage in an opaque container or dark cabinet is advised to prevent photodegradation.
- Contamination Control: Use sterilized instruments and work within a laminar-flow hood, when possible, to maintain sample sterility.
Compliance & Safety Disclaimer
This substance is provided exclusively for in-vitro laboratory research and pre-clinical developmental testing. 4 Amino Lab does not condone or authorize the use of this product in any clinical setting or for personal consumption. Misuse of laboratory chemicals carries significant health risks. By purchasing, the researcher acknowledges the inherent risks and confirms they possess the necessary equipment and expertise to handle these materials safely.
