IGF-1 LR3 1mg

Inventory Status:

Available

Product Details
AvailabilityIn stock
SKUIGF1LR3-1MG
SKU IGF1LR3-1MG Categories , Tags , , , Brand:

$70.00

Price per mg
Total (1mg)$70.00/mg

Strict Regulatory Notice: This agent is synthesized strictly for laboratory-based research and analytical purposes. It is not intended for human or veterinary use, nor for medical, household, or cosmetic applications. Please review our Terms of Service thoroughly before finalizing your acquisition.

Concentration and Formulation
Contents1mg IGF-1 LR3 per vial
ConcentrationRequires reconstitution (e.g., adding 1mL of solvent yields 1,000mcg/mL)
FormLyophilized cake/powder under vacuum

Available

For Research Use Only. Not for human or veterinary use.
Key Documents
SDS = Safety Data Sheet  ·  COA = Certificate of Analysis

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Key Specifications

ParameterSpecification / Details
Primary Compound NameIGF-1 LR3 (Insulin-like Growth Factor-1 Long Arg3)
CAS Registry Number143045-27-6
Sequence / IUPAC Equivalent83-amino acid analogue of human IGF-1 (features a 13-amino-acid N-terminal extension and an Arginine substitution at position 3)
Synonyms / Trade NamesLong R3 IGF-1, LR3 IGF-1
PubChem CIDN/A (Synthetic Protein Analogue)
Molecular FormulaC₄₀₀H₆₂₅N₁₁₁O₁₁₅S₆
Molar Mass / Weight~9111.4 g/mol
Physical AppearanceWhite lyophilized (freeze-dried) solid/powder
Solubility ProfileBest reconstituted in dilute Acetic Acid (0.6% or 100mM) to preserve receptor affinity, or Bacteriostatic Water
Tested Purity≥99% via HPLC
Active Ingredient (Total)1mg IGF-1 LR3 per vial
Dry / Powder FormulationsLyophilized cake/powder under vacuum
Liquid / Solution ConcentrationsRequires reconstitution (e.g., adding 1mL of solvent yields 1,000mcg/mL)
Alternative FormulationsIGF-1 DES (a truncated, shorter half-life variant)
Storage GuidelinesLyophilized: Store at -20°C for long-term stability. Reconstituted: Must be refrigerated at 2°C to 8°C (36°F to 46°F).
Estimated Shelf Life24+ months (lyophilized). 14 to 28 days (reconstituted and refrigerated).
Safety DocumentationStandard SDS available for IGF-1 LR3 Peptide
Terms of ApplicationFor laboratory research purposes only. Not for human or veterinary use.

Foundational Scientific Overview

Foundational Scientific Overview

IGF-1 LR3 (Long R3 Insulin-like Growth Factor-I) is a prominent subject within the field of cellular hyperplasia and muscle differentiation studies. Originally synthesized to investigate the modulation of the PI3K/AKT signaling pathway, it has become a staple for researchers examining cellular growth, survival, and proliferation in nutrient-deprived in-vitro environments.

At 4-Amino-Labs, we provide this compound in a highly stable lyophilized powder to ensure experimental reproducibility. By maintaining rigorous measurement standards, we provide the consistency required for longitudinal data integrity. This compound is frequently cited in peer-reviewed literature due to its well-documented interaction with the Type 1 IGF receptor and its significantly reduced affinity for IGF-binding proteins compared to standard IGF-1.

Analytical Composition and Purity

Purity≥99%via HPLC
FormulaC400H625N111O115S6
Physical StateWhite Lyophilized Solid

Investigational Pathways

Cellular Hyperplasia
Evaluating the compound’s influence on the mitotic rate of satellite cells and myoblasts.
PI3K/AKT Activation
Observing the downstream phosphorylation events that inhibit apoptosis and promote cellular survival.
Metabolic Efficiency
Mapping the flux of glucose and amino acid transport across cellular membranes.
Binding Protein Resistance
Investigating the agent’s extended half-life and sustained receptor activation due to reduced deactivation by IGFBPs.

Laboratory Handling and Stability

Thermal Regulation
Store in a controlled, cool, and desiccated environment. Reconstitution requires a specific buffer (often 10mM HCl or acetic acid) before dilution with bacteriostatic water.
Photostability
Protect from direct UV exposure; storage in an opaque container or dark cabinet is advised to prevent photodegradation.
Hygroscopic Prevention
Ensure the seal is hermetic after every withdrawal to prevent moisture absorption and clumping.
Contamination Control
Use sterilized instruments and work within a laminar-flow hood, when possible, to maintain sample sterility.

Compliance and Safety

This substance is provided exclusively for in-vitro laboratory research and pre-clinical developmental testing. 4-Amino-Labs does not condone or authorize the use of this product in any clinical setting or for personal consumption. Misuse of laboratory chemicals carries significant health risks. By purchasing, the researcher acknowledges the inherent risks and confirms they possess the necessary equipment and expertise to handle these materials safely.

Analytical Composition & Purity Standards

  • Chemical Formula: C400H625N111O115S6
  • Physical State: White Lyophilized Solid 

Our IGF-1 LR3 (1mg) undergoes a multifaceted verification process. Each batch is subjected to independent High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS) to ensure a purity threshold of ≥ 99%. This analytical rigor ensures the absence of residual solvents, heavy metals, or cross-contaminants, providing a stable baseline for your in-vitro or pre-clinical models.

Investigational Pathways

 Researchers utilizing IGF-1 LR3 (1mg) typically focus on the following biochemical mechanisms:

  • Cellular Hyperplasia: Evaluating the compound’s influence on the mitotic rate of satellite cells and myoblasts.
  • PI3K/AKT Activation: Observing the downstream phosphorylation events that inhibit apoptosis and promote cellular survival.
  • Metabolic Efficiency: Mapping the flux of glucose and amino acid transport across cellular membranes.
  • Binding Protein Resistance: Investigating the agent’s extended half-life and sustained receptor activation due to reduced deactivation by IGFBPs.

Laboratory Handling & Stability Protocol

To maintain the molecular integrity of IGF-1 LR3 (1mg), the following storage parameters are recommended:

  • Thermal Regulation: Store in a controlled, cool, and desiccated environment. Reconstitution requires a specific buffer (often 10mM HCl or acetic acid) before dilution with bacteriostatic water.
  • Photostability: Protect from direct UV exposure; storage in an opaque container or dark cabinet is advised to prevent photodegradation.
  • Hygroscopic Prevention: Ensure the seal is hermetic after every withdrawal to prevent moisture absorption and clumping.
  • Contamination Control: Use sterilized instruments and work within a laminar-flow hood, when possible, to maintain sample sterility.

Compliance & Safety Disclaimer

This substance is provided exclusively for in-vitro laboratory research and pre-clinical developmental testing. 4-Amino-Labs does not condone or authorize the use of this product in any clinical setting or for personal consumption. Misuse of laboratory chemicals carries significant health risks. By purchasing, the researcher acknowledges the inherent risks and confirms they possess the necessary equipment and expertise to handle these materials safely.

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IGF-1 LR3 1mg