GW501516 (Cardarine)
Inventory Status:
Availability: 19 in stock
Price range: $58.00 through $70.00
Strict Regulatory Notice: This agent is synthesized strictly for laboratory-based research and analytical purposes. It is not intended for human or veterinary use, nor for medical, household, or cosmetic applications. Please review our Terms of Service thoroughly before finalizing your acquisition.
25mg/mL solution (750mg/30mL)
25mg/mL Oil (500mg/20mL)
Key Specifications
Foundational Scientific Overview
GW501516 (Cardarine) is a paramount subject within the field of cellular bioenergetics and exercise mimetic pharmacology. As a highly potent peroxisome proliferator-activated receptor delta (PPARδ) agonist, it has become a staple for researchers examining the shift from glucose oxidation to lipid oxidation, mitochondrial biogenesis, and skeletal muscle fiber type switching.
At 4 Amino Labs, we provide this complex in a highly purified format to ensure experimental reproducibility. By maintaining rigorous measurement standards, we provide the consistency required for longitudinal data integrity.
Scientific Literature Reference: The biochemical pathway of PPARδ acting as an “exercise mimetic” by fundamentally altering fuel preference at the mitochondrial level is a cornerstone of modern metabolic research. See: Narkar, V. A., et al. (2008). “AMPK and PPARdelta agonists are exercise mimetics.” Cell, 134(3), 405-415.
Analytical Composition & Purity Standards
- Chemical Formula: C21H18F3NO3S2
- Physical State: Fine White Crystalline Solid
Our GW501516 undergoes a multifaceted verification process. Each batch is subjected to independent High-Performance Liquid Chromatography (HPLC) to ensure a purity threshold of ≥ 99%. This analytical rigor ensures the absence of cross-contaminants or heavy metal degradation products.
Investigational Pathways
Researchers utilizing GW501516 typically focus on the following biochemical mechanisms:
- Substrate Preference Shifting: Evaluating the compound’s capacity to drastically upregulate fatty acid oxidation over glycolysis in myotube cultures.
- AMPK Crosstalk: Observing the synergistic activation pathways between PPARδ and AMP-activated protein kinase.
- Mitochondrial Biogenesis: Mapping the increased density and efficiency of mitochondria in isolated skeletal muscle models.
- Fiber Type Reprogramming: Investigating the transcriptional shift from fast-twitch (Type IIx) to slow-twitch (Type I) muscle fibers in-vitro.
Laboratory Handling & Stability Protocol
To maintain the molecular integrity of GW501516, the following storage parameters are recommended:
- Thermal Regulation: Store in a controlled, cool, and desiccated environment.
- Photostability: Protect from direct UV exposure; storage in an opaque container or dark cabinet is advised.
- Contamination Control: Use sterilized instruments and work within a laminar-flow hood, when possible, to maintain sample sterility.
Compliance & Safety Disclaimer
This substance is provided exclusively for in-vitro laboratory research and pre-clinical developmental testing. 4 Amino Lab does not condone or authorize the use of this product in any clinical setting or for personal consumption. Misuse of laboratory chemicals carries significant health risks. By purchasing, the researcher acknowledges the inherent risks and confirms they possess the necessary equipment and expertise to handle these materials safely.