GLP-1 SE 5mg
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Availability: Available
$95.00
Strict Regulatory Notice: This agent is synthesized strictly for laboratory-based research and analytical purposes. It is not intended for human or veterinary use, nor for medical, household, or cosmetic applications. Please review our Terms of Service thoroughly before finalizing your acquisition.
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Key Specifications
| Parameter | Specification / Details |
|---|---|
| Primary Compound Name | Semaglutide (Single GLP-1 Receptor Agonist) |
| CAS Registry Number | 910463-68-2 |
| IUPAC Designation | (Polypeptide sequence of 31 amino acids featuring a C18 fatty diacid side chain at the Lys26 position) |
| Synonyms / Trade Names | GLP-1 SE, NN9535 |
| PubChem CID | 56843331 |
| Molecular Formula | C187H291N45O59 |
| Molar Mass / Weight | 4113.6 g/mol |
| Physical Appearance | White lyophilized (freeze-dried) solid/powder |
| Solubility Profile | Highly soluble in Bacteriostatic Water and sterile water. |
| Tested Purity | ≥98% via HPLC |
| Active Ingredient (Total) | 5mg per vial |
| Dry / Powder Formulations | Lyophilized powder |
| Alternative Formulations | Tirzepatide (Dual Agonist), Retatrutide (Triple Agonist) |
| Storage Guidelines | Lyophilized: Store at -20°C for long-term stability. Protect from light.Reconstituted: Must be refrigerated at 2°C to 8°C. |
| Estimated Shelf Life | 24 months from manufacture date (lyophilized). |
| Safety Documentation | Standard SDS available for Semaglutide |
| Terms of Application | For laboratory research purposes only. Not for human or veterinary use. Investigated as a potent, long-acting single agonist to study the isolated modulation of the glucagon-like peptide-1 receptor (GLP-1R), evaluating its role in glucose-dependent insulinotropic signaling and delayed gastric emptying in in-vitro and cellular models. |
Foundational Scientific Overview
GLP-1 SE (5mg) is a prominent subject within the field of incretin research and metabolic endocrinology. Synthesized as a highly stable, long-acting glucagon-like peptide-1 (GLP-1) receptor agonist, it serves researchers examining glucose-dependent insulinotropic pathways, gastric emptying modulation, and pancreatic beta-cell proliferation.
At 4 Amino Labs, we provide this compound in a highly purified lyophilized format to ensure experimental reproducibility. By maintaining rigorous measurement standards, we provide the consistency required for longitudinal data integrity.
Scientific Literature Reference: The biochemical pathway of acylated GLP-1 analogs providing extended half-lives and potent glycemic control via specific incretin receptor binding is a cornerstone of modern metabolic study. See: Knudsen, L. B., et al. (2000). “Potent derivatives of glucagon-like peptide-1 with pharmacokinetic properties suitable for once daily administration.” Journal of Medicinal Chemistry, 43(9), 1664-1669.
Analytical Composition & Purity Standards
- Chemical Formula: Proprietary Acylated GLP-1 Analog
- Physical State: White Lyophilized Solid
Our GLP-1 SE (5mg) undergoes a multifaceted verification process. Each batch is subjected to independent High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS) to ensure a purity threshold of ≥ 99%. This analytical rigor ensures the absolute absence of truncated peptide chains.
Investigational Pathways
Researchers utilizing GLP-1 SE typically focus on the following biochemical mechanisms:
- Receptor Kinetics: Evaluating the compound’s binding affinity and extended residency time at the GLP-1 receptor.
- Insulin Secretion: Observing the downstream cyclic AMP (cAMP) accumulation leading to glucose-dependent insulin release in isolated pancreatic islets.
- Beta-Cell Viability: Mapping the flux of anti-apoptotic markers and cellular proliferation in lipotoxic pre-clinical models.
Laboratory Handling & Stability Protocol
To maintain the molecular integrity of GLP-1 SE, the following storage parameters are recommended:
- Thermal Regulation: Store in a strictly controlled, refrigerated, and desiccated environment. Reconstituted peptides must remain cold.
- Photostability: Protect from direct UV exposure; storage in an opaque container is advised.
- Contamination Control: Utilize sterilized instruments and work within a laminar flow hood where possible.
Compliance & Safety Disclaimer
This substance is provided exclusively for in-vitro laboratory research and pre-clinical developmental testing. 4 Amino Lab does not condone or authorize the use of this product in any clinical setting or for personal consumption. Misuse of laboratory chemicals carries significant health risks. By purchasing, the researcher acknowledges the inherent risks and confirms they possess the necessary equipment and expertise to handle these materials safely.
