RAD140 (Testolone)
Inventory Status:
Availability: Available
$52.00
Strict Regulatory Notice: This agent is synthesized strictly for laboratory-based research and analytical purposes. It is not intended for human or veterinary use, nor for medical, household, or cosmetic applications. Please review our Terms of Service thoroughly before finalizing your acquisition.
20mg/mL solution (600mg/30mL)
20mg/mL Oil (400mg/20mL)
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Key Specifications
| Parameter | Specification / Details |
|---|---|
| Primary Compound Name | RAD140 (Selective Androgen Receptor Modulator) |
| CAS Registry Number | 1182367-47-0 |
| IUPAC Designation | 2-chloro-4-[[(1R,2S)-1-[5-(4-cyanophenyl)-1,3,4-oxadiazol-2-yl]-2-hydroxypropyl]amino]-3-methylbenzonitrile |
| Synonyms / Trade Names | Testolone, RAD-140 |
| PubChem CID | 44200882 |
| Molecular Formula | C₂₀H₁₆ClN₅O₂ |
| Molar Mass / Weight | 393.83 g/mol |
| Physical Appearance | White to off-white crystalline powder (raw) / Clear or slightly tinted liquid (suspended) |
| Solubility Profile | Soluble in DMSO, Ethanol, and Propylene Glycol/PEG 400. Insoluble in water. |
| Tested Purity | ≥99% via HPLC |
| Active Ingredient (Total) | 300mg per 30mL vial |
| Dry / Powder Formulations | N/A (Liquid suspension) |
| Liquid / Solution Concentrations | 10mg/mL in a PEG 400 / Ethanol carrier |
| Alternative Formulations | RAD-150 (TLB-150 Benzoate - an esterified derivative) |
| Storage Guidelines | Store at room temperature (20°C to 25°C). Protect strictly from moisture, heat, and direct sunlight. |
| Estimated Shelf Life | 24 months from manufacture date. |
| Safety Documentation | Standard SDS available for RAD140 |
| Terms of Application | For laboratory research purposes only. Not for human or veterinary use. Investigated for its highly specific affinity for the androgen receptor to evaluate tissue-selective anabolic activity in muscle and bone in-vitro models without systemic androgenic conversion. |
Foundational Scientific Overview
RAD-140 (Testolone) is a paramount subject within the field of neuroendocrinology and profound musculoskeletal anabolism. Synthesized as a highly potent, non-steroidal SARM, it serves researchers examining exceptional anabolic-to-androgenic ratios and unique neuroprotective properties independent of standard AR-mediated muscle hypertrophy.
At 4 Amino Labs, we provide this compound in a pre-suspended, highly stable 20mg/ml liquid format to ensure exact volumetric dosing and experimental reproducibility.
Scientific Literature Reference: The biochemical capacity of RAD-140 to exert immense anabolic effects while simultaneously providing potent neuroprotection in the central nervous system is highly documented. See: Jayaraman, A., et al. (2014). “Selective androgen receptor modulator RAD140 is neuroprotective in cultured neurons and kainate-lesioned male rats.” Endocrinology, 155(4), 1398-1406.
Analytical Composition & Purity Standards
- Chemical Formula: C20H16ClN5O2
- Physical State: Clear to Pale-Yellow Solution (20mg/ml)
Our RAD-140 undergoes a multifaceted verification process. Each batch is subjected to independent High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS) to ensure a purity threshold of ≥ 99%.
Investigational Pathways
Researchers utilizing RAD-140 typically focus on the following biochemical mechanisms:
- High-Affinity AR Agonism: Evaluating the compound’s profound binding kinetics and transcriptional activation in myocyte cultures, matching or exceeding steroidal baselines.
- Neuroprotective Cascades: Observing the prevention of apoptosis and the maintenance of cell viability in hippocampal neurons exposed to excitotoxins (e.g., kainate).
- Prostate Atrophy Modeling: Mapping the compound’s capacity to functionally antagonize the stimulatory effects of exogenous testosterone on seminal vesicles and prostate tissue in-vitro.
Laboratory Handling & Stability Protocol
To maintain the molecular integrity of RAD-140, the following storage parameters are recommended:
- Thermal Regulation: Store in a controlled, room-temperature environment (20°C to 25°C). Do not freeze the solution.
- Photostability: Protect from direct UV exposure; storage in an opaque container or dark cabinet is strictly advised.
- Contamination Control: Utilize sterilized instruments and work within a laminar flow hood where possible.
Compliance & Safety Disclaimer
This substance is provided exclusively for in-vitro laboratory research and pre-clinical developmental testing. 4 Amino Lab does not condone or authorize the use of this product in any clinical setting or for personal consumption. Misuse of laboratory chemicals carries significant health risks. By purchasing, the researcher acknowledges the inherent risks and confirms they possess the necessary equipment and expertise to handle these materials safely.
