SR9009 (Stenabolic)
Inventory Status:
Available
$65.00
Strict Regulatory Notice: This agent is synthesized strictly for laboratory-based research and analytical purposes. It is not intended for human or veterinary use, nor for medical, household, or cosmetic applications. Please review our Terms of Service thoroughly before finalizing your acquisition.
30mg/mL Solution (900mg/30mL)
30mg/mL Oil (600mg/20mL)
Guaranteed Safe Checkout:
Key Specifications
| Parameter | Specification / Details |
|---|---|
| Primary Compound Name | SR9009 (REV-ERB Agonist) |
| CAS Registry Number | 1379686-30-2 |
| IUPAC Designation | ethyl 3-[[[(4-chlorophenyl)methyl][(5-nitrothiophen-2-yl)methyl]amino]methyl]pyrrolidine-1-carboxylate |
| Synonyms / Trade Names | Stenabolic, SR-9009 |
| PubChem CID | 71765050 |
| Molecular Formula | C₂₀H₂₄ClN₃O₄S |
| Molar Mass / Weight | 437.94 g/mol |
| Physical Appearance | White to off-white crystalline powder (raw) / Clear or slightly tinted liquid (suspended) |
| Solubility Profile | Soluble in DMSO, Ethanol, and Propylene Glycol/PEG 400. Insoluble in water. |
| Tested Purity | ≥98% via HPLC |
| Active Ingredient (Total) | 600mg per 30mL vial |
| Dry / Powder Formulations | N/A (Liquid suspension) |
| Liquid / Solution Concentrations | 20mg/mL in a PEG 400 / Ethanol carrier |
| Alternative Formulations | SR9011 (a closely related REV-ERB agonist) |
| Storage Guidelines | Store at room temperature (20°C to 25°C). Protect strictly from moisture, heat, and direct sunlight. |
| Estimated Shelf Life | 24 months from manufacture date. |
| Safety Documentation | Standard SDS available for SR9009 |
| Terms of Application | For laboratory research purposes only. Not for human or veterinary use. Investigated for its role as a REV-ERBα and REV-ERBβ agonist to study circadian rhythm regulation, lipid metabolism, and mitochondrial biogenesis in in-vitro models. |
Foundational Scientific Overview
SR9009 (Stenabolic) is a prominent subject within the field of chronobiology, mitochondrial biogenesis, and lipid metabolism. Synthesized as a highly specific agonist for the Rev-ErbAɑ and Rev-Erbβ nuclear receptors, it has become a staple for researchers examining the genomic synchronization of the circadian rhythm with cellular energy expenditure.
At 4 Amino Labs, we provide this non-hormonal compound in a highly purified format to ensure experimental reproducibility. By maintaining rigorous measurement standards, we provide the consistency required for longitudinal data integrity.
Scientific Literature Reference: The interaction between synthetic Rev-Erb agonists and the profound alteration of circadian behavior, cholesterol metabolism, and exercise endurance is deeply documented. See: Solt, L. A., et al. (2012). “Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists.” Nature, 485(7396), 62-68.
Analytical Composition & Purity Standards
- Chemical Formula: C20H24ClN3O4S
- Physical State: Fine White to Off-White Crystalline Powder
Our SR9009 undergoes a multifaceted verification process. Each batch is subjected to independent High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS) to ensure a purity threshold of ≥ 99%.
Investigational Pathways
Researchers utilizing SR9009 typically focus on the following biochemical mechanisms:
- Rev-ErbA Activation: Evaluating the compound’s influence on repressing specific metabolic genes involved in lipid and glucose storage.
- Circadian Synchronization: Observing the modulation of core clock genes (e.g., BMAL1) in disrupted or asynchronous cellular models.
- Mitochondrial Density: Mapping the profound increase in mitochondrial genesis and macrophage cholesterol efflux in-vitro.
- Lipogenesis Inhibition: Investigating the reduction of de novo lipogenesis in isolated hepatic cells.
Laboratory Handling & Stability Protocol
To maintain the molecular integrity of SR9009, the following storage parameters are recommended:
- Thermal Regulation: Store in a strictly controlled, desiccated environment at room temperature.
- Photostability: Protect from direct UV exposure; storage in an opaque container is advised.
- Contamination Control: Use sterilized instruments and work within a laminar-flow hood, when possible, to maintain sample sterility.
Compliance & Safety Disclaimer
This substance is provided exclusively for in-vitro laboratory research and pre-clinical developmental testing. 4 Amino Lab does not condone or authorize the use of this product in any clinical setting or for personal consumption. Misuse of laboratory chemicals carries significant health risks. By purchasing, the researcher acknowledges the inherent risks and confirms they possess the necessary equipment and expertise to handle these materials safely.
