RU58841
Inventory Status:
Out of stock
$30.00
Strict Regulatory Notice: This agent is synthesized strictly for laboratory-based research and analytical purposes. It is not intended for human or veterinary use, nor for medical, household, or cosmetic applications. Please review our Terms of Service thoroughly before finalizing your acquisition.
80mg/ml solution (2400mg/30mL)
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Key Specifications
| Parameter | Specification / Details |
|---|---|
| Primary Compound Name | RU58841 (Non-Steroidal Antiandrogen) |
| CAS Registry Number | 154992-24-2 |
| IUPAC Designation | 4-[3-(4-hydroxybutyl)-4,4-dimethyl-2,5-dioxoimidazolidin-1-yl]-2-(trifluoromethyl)benzonitrile |
| Synonyms / Trade Names | PSK-3841, HMR-3841 |
| PubChem CID | 9813759 |
| Molecular Formula | C17H18F3N3O3 |
| Molar Mass / Weight | 369.34 g/mol |
| Physical Appearance | White to pale yellow crystalline powder (raw) / Clear liquid (suspended) |
| Solubility Profile | Soluble in Ethanol, DMSO, and Propylene Glycol. Insoluble in water. |
| Tested Purity | ≥99% via HPLC |
| Active Ingredient (Total) | 1,500mg per 30mL vial |
| Dry / Powder Formulations | N/A (Liquid suspension) |
| Liquid / Solution Concentrations | 50mg/mL (5%) in an Ethanol / Propylene Glycol carrier |
| Alternative Formulations | Pyrilutamide (KX-826), CB-03-01 (Breezula) |
| Storage Guidelines | Store at room temperature (20°C to 25°C). For long-term storage of raw powder, keep at -20°C. Protect strictly from moisture, heat, and direct sunlight. |
| Estimated Shelf Life | 24 months from manufacture date. |
| Safety Documentation | Standard SDS available for RU58841 |
| Terms of Application | For laboratory research purposes only. Not for human or veterinary use. Investigated for its localized, high-affinity competitive antagonism of the androgen receptor, evaluating its ability to block DHT and testosterone binding in localized cellular assays (e.g., dermal papilla models) without systemic downstream effects. |
Foundational Scientific Overview
RU58841 (PSK-3841) is a prominent subject within the field of dermatological research and endocrinology. Formulated as a non-steroidal anti-androgen (NSAA), it has become a staple for researchers examining the localized competitive inhibition of the androgen receptor (AR), particularly in isolated dermal papilla cells and hair follicle models.
At 4 Amino Labs, we provide this compound in a highly pure, raw powder or stabilized solvent format to ensure experimental reproducibility. By maintaining rigorous measurement standards, we provide the consistency required for longitudinal data integrity.
Analytical Composition & Purity Standards
- Chemical Formula: C17H18F3N3O3
- Physical State: Fine White Crystalline Solid
Our RU58841 undergoes a multifaceted verification process. Each batch is subjected to independent High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS) to ensure a purity threshold of ≥ 99%. This analytical rigor ensures the absence of systemic steroidal contaminants, providing a stable baseline for localized in-vitro models.
Investigational Pathways
Researchers utilizing RU58841 typically focus on the following biochemical mechanisms:
- Competitive AR Binding: Evaluating the compound’s affinity to outcompete Dihydrotestosterone (DHT) and Testosterone at the cellular receptor level.
- Follicular Viability: Observing the prevention of miniaturization and apoptosis in cultured hair follicle assays exposed to high androgen levels.
- Transcriptional Blockade: Mapping the inhibition of downstream gene transcription typically triggered by AR activation.
- Localized Metabolism: Investigating the rapid breakdown of the non-steroidal compound in tissue to prevent systemic carry-over.
Laboratory Handling & Stability Protocol
To maintain the molecular integrity of RU58841, the following storage parameters are recommended:
- Thermal Regulation: Store in a strictly controlled, refrigerated environment.
- Solvent Compatibility: Typically reconstituted in a vehicle of ethanol and propylene glycol for topical/dermal assays.
- Photostability: Protect from direct UV exposure; storage in an opaque container is advised.
- Contamination Control: Use sterilized instruments and work within a laminar-flow hood, when possible, to maintain sample sterility.
Compliance & Safety Disclaimer
This substance is provided exclusively for in-vitro laboratory research and pre-clinical developmental testing. 4 Amino Lab does not condone or authorize the use of this product in any clinical setting or for personal consumption. Misuse of laboratory chemicals carries significant health risks. By purchasing, the researcher acknowledges the inherent risks and confirms they possess the necessary equipment and expertise to handle these materials safely.
