Lipotropic(MIC) + B12 30ml
Inventory Status:
Availability: Available
$63.00
Strict Regulatory Notice: This agent is synthesized strictly for laboratory-based research and analytical purposes. It is not intended for human or veterinary use, nor for medical, household, or cosmetic applications. Please review our Terms of Service thoroughly before finalizing your acquisition.
Composition: Each mL of sterile aqueous solution contains:
Active Ingredients:
Methylcobalamin (B12)………………1000 mcg
Methionine……………………………………25 mg
Inositol…………………………………………..50 mg
Choline…………………………………………..25 mg
Inactive Ingredients: Benzyl Alcohol 1.5% v/v as preservative, Ammonium Sulfate 0.1
Availability: Available
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Key Specifications
| Parameter | Specification / Details |
|---|---|
| Primary Compound Name | Lipotropic MIC + B12 (Lipo-B Assay) |
| Component 1 | L-Methionine (Essential Sulfur-containing Amino Acid) |
| Component 2 | Inositol (Vitamin-like Cyclitol) |
| Component 3 | Choline Chloride (Essential Nutrient/Phospholipid Precursor) |
| Component 4 | Cyanocobalamin (Vitamin B12) |
| Physical Appearance | Clear, vibrant red aqueous solution (due to B12) |
| Solubility Profile | Fully miscible aqueous solution |
| Concentration (per mL) | Methionine: 25mgInositol: 50mgCholine: 50mgB12: 1mg (1000mcg) |
| Total Package Yield | 750mg Methionine / 1500mg Inositol / 1500mg Choline / 30mg B12 per 30mL |
| Inactive Ingredients | Benzyl Alcohol (preservative), Sodium Hydroxide/HCl (pH adjusters), Water for Injection |
| Storage Guidelines | Store at 20°C to 25°C. Photosensitive: Protect strictly from direct light to prevent B12 degradation. |
| Estimated Shelf Life | 24 months from manufacture date. |
| Safety Documentation | Standard SDS available for MIC-B12 compounds |
| Terms of Application | For laboratory research purposes only. Investigated for its role in "One-Carbon Metabolism" and the methionine cycle. Studied for the synergistic regulation of hepatic fat mobilization via S-adenosylmethionine (SAMe) synthesis, phosphatidylcholine production for VLDL assembly, and mitochondrial energy flux in in-vitro hepatocyte models. |
Foundational Scientific Overview
Lipotropic MIC B12 (30ml) is a prominent subject within the field of hepatic lipid metabolism and methyl-donor pathways. Formulated as a precise blend of Methionine, Inositol, Choline, and Cyanocobalamin (B12), it has become a staple for researchers examining the mobilization of hepatic triglycerides, cellular methylation, and transsulfuration cascades.
At 4 Amino Labs, we provide this compound in a highly stable aqueous format to ensure experimental reproducibility. By maintaining rigorous measurement standards, we provide the consistency required for longitudinal data integrity.
Scientific Literature Reference: The critical roles of choline and methionine in hepatic lipid export and cellular methylation are deeply established. See: Zeisel, S. H. (2006). “Choline: critical role during fetal development and dietary requirements in adults.” Annual Review of Nutrition, 26, 229-250. and Finkelstein, J. D. (1990). “Methionine metabolism in mammals.” The Journal of Nutritional Biochemistry, 1(5), 228-237.
Analytical Composition & Purity Standards
- Chemical Formula: Multi-Substrate Lipotropic Complex (C5H11NO2S, C6H12O6, C5H14NO, C63H88CoN14O14P)
- Physical State: Red Aqueous Solution
Our Lipotropic MIC B12 undergoes a multifaceted verification process. Each batch is subjected to independent High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS) to verify the precise stoichiometric ratio of the blend, ensuring a collective purity threshold of ≥ 99%.
Investigational Pathways
Researchers utilizing Lipotropic MIC B12 typically focus on the following biochemical mechanisms:
- Hepatic Lipid Export: Evaluating the compound’s role in upregulating the synthesis of very-low-density lipoproteins (VLDL) to clear triglycerides from isolated hepatocyte models.
- Methylation Cycles: Observing the conversion of homocysteine to methionine and the generation of S-adenosylmethionine (SAMe).
- Cellular Membrane Integrity: Mapping the flux of phosphatidylcholine synthesis mediated by the inositol and choline constituents.
- Mitochondrial Bioenergetics: Investigating the synergistic role of B12 as a coenzyme in the methylmalonyl-CoA mutase pathway.
lular models.
Laboratory Handling & Stability Protocol
To maintain the molecular integrity of Lipotropic MIC B12, the following storage parameters are recommended:
- Thermal Regulation: Store in a controlled room-temperature environment (20°C to 25°C). Avoid excessive heat and do not freeze.
- Photostability: The B12 constituent is highly photosensitive. Storage in an opaque container or dark cabinet is strictly advised to prevent cleavage of the cobalt bonds.
- Contamination Control: Use sterilized instruments and work within a laminar-flow hood, when possible, to maintain sample sterility.
Compliance & Safety Disclaimer
This substance is provided exclusively for in-vitro laboratory research and pre-clinical developmental testing. 4 Amino Lab does not condone or authorize the use of this product in any clinical setting or for personal consumption. Misuse of laboratory chemicals carries significant health risks. By purchasing, the researcher acknowledges the inherent risks and confirms they possess the necessary equipment and expertise to handle these materials safely.
