SR9011
Inventory Status:
Available
$72.00
Strict Regulatory Notice: This agent is synthesized strictly for laboratory-based research and analytical purposes. It is not intended for human or veterinary use, nor for medical, household, or cosmetic applications. Please review our Terms of Service thoroughly before finalizing your acquisition.
20mg/mL solution (600mg/30mL)
Guaranteed Safe Checkout:
Key Specifications
| Parameter | Specification / Details |
|---|---|
| Primary Compound Name | SR9011 (REV-ERB Agonist) |
| CAS Registry Number | 1379686-29-9 |
| IUPAC Designation | 3-[[[(4-chlorophenyl)methyl][(5-nitrothiophen-2-yl)methyl]amino]methyl]-N-pentylpyrrolidine-1-carboxamide |
| Synonyms / Trade Names | Stenabolic SR9011 |
| PubChem CID | 57394021 |
| Molecular Formula | C₂₃H₃₁ClN₄O₃S |
| Molar Mass / Weight | 479.04 g/mol |
| Physical Appearance | Clear or slightly tinted liquid |
| Solubility Profile | Soluble in DMSO, Ethanol, and Propylene Glycol/PEG 400. Insoluble in water. |
| Tested Purity | ≥98% via HPLC |
| Active Ingredient (Total) | 600mg per 30mL vial |
| Dry / Powder Formulations | N/A (Liquid suspension) |
| Liquid / Solution Concentrations | 20mg/mL in a PEG 400 / Ethanol carrier |
| Alternative Formulations | SR9009 (Stenabolic - a closely related REV-ERB agonist) |
| Storage Guidelines | Store at room temperature (20°C to 25°C). Protect from moisture, heat, and direct sunlight. |
| Estimated Shelf Life | 24 months from manufacture date. |
| Safety Documentation | Standard SDS available for SR9011 |
| Terms of Application | For laboratory research purposes only. Not for human or veterinary use. |
Foundational Scientific Overview
SR9011 is a paramount subject within the field of chronobiology and metabolic transcription. As a highly specific Rev-ErbA agonist, closely related structurally and functionally to SR9009, it serves researchers examining the genomic regulation of wakefulness, sleep architecture, and profound shifts in energy substrate utilization from glucose to fatty acids.
At 4 Amino Labs, we provide this compound in a highly pure format to ensure experimental reproducibility. By maintaining rigorous measurement standards, we provide the consistency required for longitudinal data integrity.
Scientific Literature Reference: The biochemical capacity of SR9011 to reduce fat mass and improve dyslipidemia through Rev-Erb activation, independent of locomotor activity, is highly established. See: Solt, L. A., et al. (2012). “Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists.” Nature, 485(7396), 62-68.
Analytical Composition & Purity Standards
- Chemical Formula: C22H24ClN3O4S
- Physical State: Fine Crystalline Solid
Our SR9011 undergoes a multifaceted verification process. Each batch is subjected to independent High-Performance Liquid Chromatography (HPLC) to ensure a purity threshold of ≥ 99%.
Investigational Pathways
Researchers utilizing SR9011 typically focus on the following biochemical mechanisms:
- Sleep Architecture Modeling: Evaluating the compound’s capacity to suppress REM sleep and alter slow-wave sleep phases via circadian clock gene modulation.
- Autophagy & Macrophage Function: Observing the enhancement of cellular clearance pathways and the reduction of inflammatory cytokine production.
- Substrate Shifting: Mapping the total inhibition of lipogenic enzymes and the immediate upregulation of fatty acid oxidation in skeletal muscle cultures.
Laboratory Handling & Stability Protocol
To maintain the molecular integrity of SR9011, the following storage parameters are recommended:
- Thermal Regulation: Store in a controlled, cool, and desiccated environment.
- Photostability: Protect from direct UV exposure; storage in an opaque container or dark cabinet is strictly advised.
- Contamination Control: Use sterilized instruments and work within a laminar-flow hood, when possible, to maintain sample sterility.
Compliance & Safety Disclaimer
This substance is provided exclusively for in-vitro laboratory research and pre-clinical developmental testing. 4 Amino Lab does not condone or authorize the use of this product in any clinical setting or for personal consumption. Misuse of laboratory chemicals carries significant health risks. By purchasing, the researcher acknowledges the inherent risks and confirms they possess the necessary equipment and expertise to handle these materials safely.
