Thozalinone

Inventory Status:

Out of stock

$110.00

Strict Regulatory Notice: This agent is synthesized strictly for laboratory-based research and analytical purposes. It is not intended for human or veterinary use, nor for medical, household, or cosmetic applications. Please review our Terms of Service thoroughly before finalizing your acquisition.

Thozalinone (tozalinone, CAS 655-05-0) for laboratory research: 50 tablets at approximately 50mg each. Pemoline-analog 2-oxazolinone reference compound for catecholamine release research, with Certificate of Analysis and Safety Data Sheet.

Tablet Concentration 50 Tablets (~50 mg/Tablet, 2,500 mg total, laboratory reference use only)

Inactive Ingredients: Microcrystalline cellulose, Magnesium stearate, Dicalcium phosphate, Silicon dioxide

For Research Use Only. Not for human or veterinary use

Out of stock

Email when stock available

Guaranteed Safe Checkout:

payment icons.jpg

Key Specifications

ParameterSpecification / Details
Primary Compound NameThozalinone (2-Oxazolinone Derivative)
CAS Registry Number655-05-0
IUPAC Designation2-(Dimethylamino)-5-phenyl-1,3-oxazol-4(5H)-one
SynonymsTozalinone, Stimsen, CL-39808, NSC 170962, 2-(Dimethylamino)-5-phenyl-2-oxazolin-4-one
Molecular FormulaC11H12N2O2
Molar Mass / Weight204.23 g/mol
Compound Class2-Oxazolinone derivative / pemoline analog (racemic)
Physical AppearanceWhite tablet (raw material: white to off-white crystalline powder)
Melting Point (raw material)133–136 °C
Tested PurityBatch-specific, reported by HPLC on the Certificate of Analysis
Tablet Concentration~50mg per tablet, 50 tablets (2,500mg total)
Inactive Ingredients (Tablets)Microcrystalline cellulose, Magnesium stearate, Dicalcium phosphate, Silicon dioxide
Related CompoundsPemoline, Fenozolone, Aminorex
Storage GuidelinesCool, dry, tightly closed, protected from light and moisture; 2–8°C for long-term storage.
Estimated Shelf Life24 months from manufacture date when stored as directed.
Safety DocumentationSDS available for Thozalinone 50 mg Tablets
Terms of ApplicationFor laboratory research purposes only. Not for human or veterinary use. Investigated as a catecholamine-releasing reference compound in dopaminergic and noradrenergic signaling models.

Foundational Scientific Overview

Thozalinone (2-(dimethylamino)-5-phenyl-4(5H)-oxazolone) is a 2-oxazolinone derivative and a structural analog of pemoline. Also catalogued as tozalinone, Stimsen and CL-39808, it has become a reference compound for researchers examining catecholamine release, dopaminergic and noradrenergic signaling, and structure-activity relationships within the oxazolone class.

At 4 Amino Lab, we provide this compound in 50mg tablets (50 count, 2,500mg total) to ensure experimental reproducibility. By maintaining rigorous measurement standards, we provide the consistency required for longitudinal data integrity. Thozalinone appears in the published pharmacology literature as a dopamine-releasing compound with a smaller norepinephrine component, and in analytical chemistry as a reference standard alongside pemoline and fenozolone.

Analytical Composition & Purity Standards

  • Chemical Formula: C11H12N2O2
  • Molecular Weight: 204.23 g/mol
  • Stereochemistry: Racemic (one undefined stereocenter at C-5)
  • Appearance (raw material): White to off-white crystalline powder
  • Melting Point (raw material): 133–136 °C
  • Solubility: Soluble in DMSO and PEG-400; limited solubility in water
  • Stability: Stable under cool, dry, dark laboratory storage; protect from moisture.

Our Thozalinone undergoes a multifaceted verification process. Each batch is submitted for independent High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS) testing to confirm identity and document chromatographic purity, with results published on the batch Certificate of Analysis. This analytical rigor provides a stable, documented baseline for your in-vitro or pre-clinical models. Researchers looking to buy thozalinone tablets often prioritize verified identity, documented purity and consistent tablet mass.

Investigational Pathways

Researchers utilizing Thozalinone typically focus on the following biochemical mechanisms:

Thozalinone is commonly examined in neurochemistry and monoamine signaling research, particularly in studies involving:

  • Dopamine release and catecholamine efflux in in-vitro and pre-clinical models
  • Noradrenergic signaling and norepinephrine release kinetics
  • Comparative pharmacology of oxazolone-class compounds (pemoline, fenozolone, thozalinone)
  • Structure-activity relationships of 2-amino-oxazol-4-one derivatives
  • Analytical method development for chromatographic separation of oxazolone stimulants

Because it shares a scaffold with pemoline while differing in its amine substitution, thozalinone is useful as a comparator for isolating how small structural changes alter catecholamine release in controlled models.

Laboratory Handling & Stability Protocol

To maintain the molecular integrity of Thozalinone, the following storage parameters are
recommended:

  1. Thermal Regulation: Store tablets in a cool, desiccated environment at controlled room temperature (20–25°C); refrigeration at 2–8°C is suitable for long-term storage. Allow the bottle to reach room temperature before opening to avoid condensation.
  2. Moisture Control: The oxazolone ring can be susceptible to hydrolysis. Keep the desiccant in the bottle and avoid humid environments.
  3. Photostability: Keep in the original opaque container, away from direct light.
  4. Seal Integrity: Ensure the cap is tightly closed after every use to prevent moisture absorption.
  5. Containment: Wear nitrile gloves, and crush, split, or weigh tablets only in a fume hood or ventilated enclosure. Review the Safety Data Sheet before handling.

Compliance & Safety Disclaimer

Thozalinone is supplied strictly as a Research Use Only (RUO) laboratory reference compound for in-vitro and pre-clinical investigation. It is not a drug, dietary supplement, or approved medicine, and is not for human or veterinary use. Thozalinone is a pharmacologically active central nervous system research compound and is treated as harmful if swallowed (see Safety Data Sheet). Handle only by qualified personnel with appropriate protective equipment, keep out of reach of unauthorized persons, and dispose of waste through a licensed contractor. Purchasers are responsible for complying with all local, state and federal regulations that apply to their research.

0
Please choose an option first.
Thozalinone