Livagen (20mg)

Inventory Status:
Available

SKU Livagen Categories Bioregulators, Short Chains Amino Acids Brand: 4-Amino-Labs

$70.00

Strict Regulatory Notice: This agent is synthesized strictly for laboratory-based research and analytical purposes. It is not intended for human or veterinary use, nor for medical, household, or cosmetic applications. Please review our Terms of Service thoroughly before finalizing your acquisition.

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Key Specifications

Category	Parameter	Specification / Details
Identification & Nomenclature	Primary Compound Name	Livagen (Chromatin Bioregulator)
	CAS Registry Number	Khavinson Synthetic Tetrapeptide
	Sequence / IUPAC	Lys-Glu-Asp-Ala
Chemical & Physical Properties	Molecular Formula	C18H31N5O9
	Molar Mass / Weight	461.47 g/mol
	Physical Appearance	White lyophilized (freeze-dried) solid/powder
	Solubility Profile	Highly soluble in Bacteriostatic Water and sterile water.
Product Specifications	Tested Purity	≥98% via HPLC
	Active Ingredient (Total)	20mg per vial
	Dry / Powder Formulations	Lyophilized powder
Handling & Logistics	Storage Guidelines	Lyophilized: Store at -20°C for long-term stability. Protect from light.Reconstituted: Must be refrigerated at 2°C to 8°C.
	Estimated Shelf Life	24 months from manufacture date (lyophilized).
	Terms of Application	For laboratory research purposes only. Not for human or veterinary use. Investigated for its ability to de-condense heterochromatin in older cells, restoring gene expression and lymphocyte activation patterns in in-vitro models.

Foundational Scientific Overview

Livagen (20mg) is a highly specialized subject within the field of immunogerontology and epigenetic modulation. Synthesized as a targeted tetrapeptide (Lys-Glu-Asp-Ala), it serves researchers examining the profound decondensation of peri-centromeric heterochromatin, the reactivation of silenced genes in aging immune and hepatic cells, and the mitigation of cellular senescence.

At 4 Amino Labs, we provide this highly purified epigenetic regulator to ensure experimental reproducibility in sensitive chromosomal assays.

Scientific Literature Reference: The unique capacity of the Livagen tetrapeptide to induce widespread chromatin unspooling, thereby restoring the transcriptional potential of older lymphocytes, is a cornerstone of epigenetic research. See: Lezhava, T., et al. (2004). “Epigenetic modification of heterochromatin in aging: Livagen peptide induces decondensation of peri-centromeric heterochromatin in lymphocytes of old individuals.” Biogerontology, 5(2), 73-79.

Analytical Composition & Purity Standards

Chemical Formula: Proprietary Tetrapeptide (Lys-Glu-Asp-Ala)
Physical State: White Lyophilized Solid

Our Livagen undergoes a multifaceted verification process via independent High-Performance Liquid Chromatography (HPLC) to ensure a purity threshold of ≧ 99%.

Investigational Pathways

Researchers utilizing Livagen typically focus on the following biochemical mechanisms:

Chromatin Unspooling: Evaluating the structural decondensation of heterochromatin using fluorescent in situ hybridization (FISH) in cultured senescent cells.
Epigenetic Reactivation: Observing the subsequent upregulation of previously silenced genes responsible for immune system signaling and hepatic detoxification.
Lymphocyte Viability: Mapping the increase in functional capacity and apoptotic resistance in aged T-cell models.

Laboratory Handling & Stability Protocol

To maintain the molecular integrity of Livagen, the following storage parameters are recommended:

Thermal Regulation: Store in a strictly controlled, refrigerated, and desiccated environment.
Photostability: Protect from direct UV exposure; storage in an opaque container is advised.
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Compliance & Safety Disclaimer

This substance is provided exclusively for in-vitro laboratory research and pre-clinical developmental testing. 4 Amino Lab does not condone or authorize the use of this product in any clinical setting or for personal consumption. Misuse of laboratory chemicals carries significant health risks. By purchasing, the researcher acknowledges the inherent risks and confirms they possess the necessary equipment and expertise to handle these materials safely.