Thymosin Alpha-1 (10mg)
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$75.00
Strict Regulatory Notice: This agent is synthesized strictly for laboratory-based research and analytical purposes. It is not intended for human or veterinary use, nor for medical, household, or cosmetic applications. Please review our Terms of Service thoroughly before finalizing your acquisition.
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Key Specifications
| Category | Parameter | Specification / Details |
|---|---|---|
| Identification & Nomenclature | Primary Compound Name | Thymosin Alpha-1 (Immune Modulator) |
| CAS Registry Number | 62304-98-7 | |
| Sequence / IUPAC | Ac-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn-OH | |
| Chemical & Physical Properties | Molecular Formula | C129H215N33O55 |
| Molar Mass / Weight | 3108.3 g/mol | |
| Physical Appearance | White lyophilized (freeze-dried) solid/powder | |
| Solubility Profile | Highly soluble in Bacteriostatic Water and sterile water. | |
| Product Specifications | Tested Purity | ≥98% via HPLC |
| Active Ingredient (Total) | 10mg per vial | |
| Dry / Powder Formulations | Lyophilized powder | |
| Handling & Logistics | Storage Guidelines | Lyophilized: Store at -20°C for long-term stability. Protect from light.Reconstituted: Must be refrigerated at 2°C to 8°C. |
| Estimated Shelf Life | 24 months from manufacture date (lyophilized). | |
| Terms of Application | For laboratory research purposes only. Not for human or veterinary use. Investigated for the modulation of T-cell maturation, enhancement of major histocompatibility complex (MHC) class I expression, and the stimulation of cytokine production in in-vitro immune assays. |
Foundational Scientific Overview
Thymosin Alpha-1 (10mg) is a primary subject within the field of immunomodulation and infectious disease modeling. Synthesized as a highly specific 28-amino acid polypeptide naturally produced by the thymus gland, it has become a staple for researchers examining T-cell maturation, the enhancement of major histocompatibility complex (MHC) class I expression, and natural killer (NK) cell activation.
At 4 Amino Labs, we provide this highly pure sequence to ensure experimental reproducibility across varied immunological assays.
Scientific Literature Reference: The biochemical pathway of Thymosin Alpha-1 acting as a pleiotropic immune system enhancer, specifically driving the differentiation of T-helper and cytotoxic T-cells, is a cornerstone of immunology. See: Goldstein, A. L., & Badamchian, M. (2004). “Thymosin alpha 1: chemistry, macrophages, and immunomodulation.” Expert Opinion on Biological Therapy, 4(4), 559-573.
Analytical Composition & Purity Standards
- Chemical Formula: C129H215N33O55
- Physical State: White Lyophilized Solid
Our Thymosin Alpha-1 undergoes independent High-Performance Liquid Chromatography (HPLC) to ensure a purity threshold of ≧ 99%.
Investigational Pathways
Researchers utilizing Thymosin Alpha-1 typically focus on the following biochemical mechanisms:
- Dendritic Cell Activation: Evaluating the compound’s influence on toll-like receptor (TLR) signaling pathways.
- T-Cell Proliferation: Observing the upregulation of IL-2 and interferon-gamma (IFN-Ɣ) in isolated lymphocyte cultures.
- Viral & Oncological Assays: Mapping the peptide’s capacity to restore immune recognition and cytotoxicity in pathogen-infected or oncogenically transformed pre-clinical models.
Laboratory Handling & Stability Protocol
To maintain the molecular integrity of Thymosin Alpha-1, the following storage parameters are recommended:
- Thermal Regulation: Store in a controlled, desiccated environment at -20°C for optimal long-term preservation.
- Photostability: Protect from direct UV exposure.
- Contamination Control: Utilize sterilized instruments and work within a laminar flow hood where possible.
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Compliance & Safety Disclaimer
This substance is provided exclusively for in-vitro laboratory research and pre-clinical developmental testing. 4 Amino Lab does not condone or authorize the use of this product in any clinical setting or for personal consumption. Misuse of laboratory chemicals carries significant health risks. By purchasing, the researcher acknowledges the inherent risks and confirms they possess the necessary equipment and expertise to handle these materials safely.
