Available
$65.00
Strict Regulatory Notice: This agent is synthesized strictly for laboratory-based research and analytical purposes. It is not intended for human or veterinary use, nor for medical, household, or cosmetic applications. Please review our Terms of Service thoroughly before finalizing your acquisition.
Available
| Category | Parameter | Specification / Details |
|---|---|---|
| Identification & Nomenclature | Primary Compound Name | KPV (alpha-MSH Fragment) |
| CAS Registry Number | 80082-62-8 | |
| Sequence / IUPAC | Lys-Pro-Val | |
| Chemical & Physical Properties | Molecular Formula | C16H30N4O4 |
| Molar Mass / Weight | 342.43 g/mol | |
| Physical Appearance | White lyophilized (freeze-dried) solid/powder | |
| Solubility Profile | Highly soluble in Bacteriostatic Water and sterile water. | |
| Product Specifications | Tested Purity | ≥98% via HPLC |
| Active Ingredient (Total) | 10mg per vial | |
| Dry / Powder Formulations | Lyophilized powder | |
| Handling & Logistics | Storage Guidelines | Lyophilized: Store at -20°C for long-term stability. Protect from light.Reconstituted: Must be refrigerated at 2°C to 8°C. |
| Estimated Shelf Life | 24 months from manufacture date (lyophilized). | |
| Terms of Application | For laboratory research purposes only. Not for human or veterinary use. Investigated for its potent anti-inflammatory properties, particularly evaluating the inhibition of NF-kB intracellular signaling pathways in mucosal and mast cell models. |
KPV (10mg) is a paramount subject within the field of localized anti-inflammatory research and mucosal healing. Synthesized as a highly stable tripeptide (Lysine-Proline-Valine) representing the C-terminal sequence of alpha-melanocyte-stimulating hormone (ɑ-MSH), it serves researchers examining the profound down-regulation of pro-inflammatory cytokines without the melanogenic (pigment-inducing) side effects of full-length MSH.
At 4 Amino Labs, we provide this highly purified compound to ensure experimental reproducibility. By maintaining rigorous measurement standards, we provide the consistency required for longitudinal data integrity.
Scientific Literature Reference: The biochemical capacity of the KPV tripeptide to enter intestinal and epithelial cells via the PepT1 transporter and strongly inhibit NF-ΚB activation is highly documented in gastroenterological literature. See: Dalmasso, G., et al. (2008). “PepT1-mediated epithelial transport of the antimicrobial peptide KPV suppresses intestinal inflammation.” Gastroenterology, 134(1), 166-178.
Our KPV undergoes a multifaceted verification process. Each batch is subjected to independent High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS) to ensure a purity threshold of ≧ 99%.
Researchers utilizing KPV typically focus on the following biochemical mechanisms:
To maintain the molecular integrity of KPV, the following storage parameters are recommended:
This substance is provided exclusively for in-vitro laboratory research and pre-clinical developmental testing. 4 Amino Lab does not condone or authorize the use of this product in any clinical setting or for personal consumption. Misuse of laboratory chemicals carries significant health risks. By purchasing, the researcher acknowledges the inherent risks and confirms they possess the necessary equipment and expertise to handle these materials safely.
