Epithalon (10mg)
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$35.00
Strict Regulatory Notice: This agent is synthesized strictly for laboratory-based research and analytical purposes. It is not intended for human or veterinary use, nor for medical, household, or cosmetic applications. Please review our Terms of Service thoroughly before finalizing your acquisition.
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Key Specifications
| Category | Parameter | Specification / Details |
|---|---|---|
| Identification & Nomenclature | Primary Compound Name | Epithalon (Pineal Gland Bioregulator) |
| CAS Registry Number | 307297-39-8 | |
| Sequence / IUPAC | Ala-Glu-Asp-Gly | |
| Chemical & Physical Properties | Molecular Formula | C14H22N4O9 |
| Molar Mass / Weight | 390.35 g/mol | |
| Physical Appearance | White lyophilized (freeze-dried) solid/powder | |
| Solubility Profile | Highly soluble in Bacteriostatic Water and sterile water. | |
| Product Specifications | Tested Purity | ≥98% via HPLC |
| Active Ingredient (Total) | 10mg per vial | |
| Dry / Powder Formulations | Lyophilized powder | |
| Handling & Logistics | Storage Guidelines | Lyophilized: Store at -20°C for long-term stability. Protect from light.Reconstituted: Must be refrigerated at 2°C to 8°C. |
| Estimated Shelf Life | 24 months from manufacture date (lyophilized). | |
| Terms of Application | For laboratory research purposes only. Not for human or veterinary use. Investigated for the induction of telomerase activity, telomere elongation, and modulation of circadian melatonin synthesis in in-vitro and cellular aging models. |
Foundational Scientific Overview
Epithalon (10mg) is a paramount subject within the field of genomic senescence, telomerase activation, and pineal gland chronobiology. Synthesized as a highly specific tetrapeptide (Ala-Glu-Asp-Gly), it serves researchers examining the elongation of telomeres, the mitigation of chromosomal degradation, and the normalization of melatonin synthesis in-vitro.
At 4 Amino Labs, we provide this highly purified bio-regulator to ensure experimental reproducibility in sensitive aging and genomic instability assays.
Scientific Literature Reference: The profound capability of this synthetic tetrapeptide to upregulate telomerase activity, overcoming the Hayflick limit in somatic cell lines, is heavily documented in gerontological literature. See: Khavinson, V. K., et al. (2003). “Epithalon peptide induces telomerase activity and telomere elongation in human somatic cells.” Bulletin of Experimental Biology and Medicine, 135(6), 590-592.
Analytical Composition & Purity Standards
- Chemical Formula: C14H22N4O9
- Physical State: White Lyophilized Solid
Our Epithalon undergoes a multifaceted verification process via independent High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS) to ensure a purity threshold of ≧ 99%.
Investigational Pathways
Researchers utilizing Epithalon typically focus on the following biochemical mechanisms:
- Telomerase Activation: Evaluating the compound’s role in promoting the transcription of the TERT gene to restore telomere length in dividing cell cultures.
- Pineal Gland Modulation: Observing the upregulation of melatonin synthesis and the synchronization of circadian rhythms in pre-clinical models.
- Cellular Lifespan Extension: Mapping the reduction of apoptotic markers and the extension of cellular viability past normal replicative limits.
- Oxidative Stress Mitigation: Investigating the agent’s capacity to increase endogenous antioxidant enzymes (like superoxide dismutase).
Laboratory Handling & Stability Protocol
To maintain the molecular integrity of Epithalon, the following storage parameters are recommended:
- Thermal Regulation: Store in a strictly controlled, refrigerated, and desiccated environment.
- Photostability: Protect from direct UV exposure; storage in an opaque container is advised.
- Contamination Control: Utilize sterilized instruments and work within a laminar flow hood where possible.
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Compliance & Safety Disclaimer
This substance is provided exclusively for in-vitro laboratory research and pre-clinical developmental testing. 4 Amino Lab does not condone or authorize the use of this product in any clinical setting or for personal consumption. Misuse of laboratory chemicals carries significant health risks. By purchasing, the researcher acknowledges the inherent risks and confirms they possess the necessary equipment and expertise to handle these materials safely.
