GLP-3 RE 10mg
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Availability: Available
$168.00
Strict Regulatory Notice: This agent is synthesized strictly for laboratory-based research and analytical purposes. It is not intended for human or veterinary use, nor for medical, household, or cosmetic applications. Please review our Terms of Service thoroughly before finalizing your acquisition.
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Key Specifications
| Parameter | Specification / Details |
|---|---|
| Primary Compound Name | Retatrutide (Triple-Agonist Peptide) |
| CAS Registry Number | 2381089-83-2 |
| IUPAC Designation | (Sequence incorporates Aib, α-MeL, and a C20 fatty diacid moiety at position 17) |
| Synonyms / Trade Names | GLP-3 RE, LY-3437943, Triple-G Agonist |
| PubChem CID | 171390338 |
| Molecular Formula | C221H342N46O68 |
| Molar Mass / Weight | 4731.33 g/mol |
| Physical Appearance | White lyophilized (freeze-dried) solid/powder |
| Solubility Profile | Highly soluble in Bacteriostatic Water. |
| Tested Purity | ≥98% via HPLC |
| Active Ingredient (Total) | Typically 2mg, 5mg, or 10mg per vial |
| Dry / Powder Formulations | Lyophilized powder |
| Alternative Formulations | Semaglutide (GLP-1), Tirzepatide (GLP-1/GIP) |
| Storage Guidelines | Lyophilized: Store at -20°C for long-term stability. Protect from light.Reconstituted: Must be refrigerated at 2°C to 8°C. |
| Estimated Shelf Life | 24 months from manufacture date (lyophilized). |
| Safety Documentation | Standard SDS available for Retatrutide |
| Terms of Application | For laboratory research purposes only. Not for human or veterinary use. Investigated as a highly potent tri-agonist to study the synergistic metabolic regulation of the glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R) in in-vitro energy expenditure and lipid metabolism models. |
Foundational Scientific Overview
GLP-3 RE (10mg) represents the cutting edge of multi-target metabolic research. Synthesized as a tri-agonist, it concurrently activates the GLP-1, GIP, and Glucagon (GCG) receptors. It serves researchers examining complex hepatic lipid clearance, maximal energy expenditure, and systemic metabolic reprogramming in pre-clinical models.
At 4 Amino Labs, we provide this highly complex peptide to ensure experimental reproducibility across varied multi-receptor assays.
Scientific Literature Reference: The development of tri-agonists that incorporate glucagon receptor activation to drastically increase energy expenditure while utilizing GLP-1/GIP for glycemic control is highly established in recent molecular literature. See: Tschöp, M. H., et al. (2016). “Unimolecular Polypharmacy for Treatment of Diabetes and Obesity.” Cell Metabolism, 24(1), 51-62.
Analytical Composition & Purity Standards
- Chemical Formula: Proprietary Tri-Agonist Peptide Sequence
- Physical State: White Lyophilized Solid
Our GLP-3 RE undergoes a multifaceted verification process via independent High-Performance Liquid Chromatography (HPLC) to verify the precise structural integrity of the complex chain, ensuring a purity threshold of ≥ 99%.
Investigational Pathways
Researchers utilizing GLP-3 RE typically focus on the following biochemical mechanisms:
- Tri-Receptor Kinetics: Evaluating the compound’s simultaneous binding and activation thresholds across hepatic and pancreatic cell lines.
- Hepatic Steatosis Reversal: Observing the profound reduction of lipid accumulation in isolated hepatocyte models via GCG activation.
- Maximal Thermogenesis: Mapping the flux of uncoupling proteins (UCPs) and cellular energy output.
Laboratory Handling & Stability Protocol
To maintain the molecular integrity of GLP-3 RE, the following storage parameters are recommended:
- Thermal Regulation: Store in a strictly controlled, refrigerated, and desiccated environment (-20°C preferred for long-term).
- Photostability: Protect from direct UV exposure.
Compliance & Safety Disclaimer
This substance is provided exclusively for in-vitro laboratory research and pre-clinical developmental testing. 4 Amino Lab does not condone or authorize the use of this product in any clinical setting or for personal consumption. Misuse of laboratory chemicals carries significant health risks. By purchasing, the researcher acknowledges the inherent risks and confirms they possess the necessary equipment and expertise to handle these materials safely.
