NAD+ 3000mg
Inventory Status:
Availability: 67 in stock
$75.00
Strict Regulatory Notice: This agent is synthesized strictly for laboratory-based research and analytical purposes. It is not intended for human or veterinary use, nor for medical, household, or cosmetic applications. Please review our Terms of Service thoroughly before finalizing your acquisition.
Composition: Each mL of sterile aqueous solution contains:
Active Ingredients:
NAD+ (nicotinamide adenine dinucleotide) ……….100 mg (3,000mg/Vial)
Inactive Ingredients: Benzyl Alcohol 1.5% v/v as preservative, Ammonium Sulfate 0.1%.
Availability: 67 in stock
Key Specifications
Foundational Scientific Overview
NAD+ (Nicotinamide Adenine Dinucleotide) is a paramount subject within the field of redox biology, cellular aging, and epigenetics. Serving as a universal electron transporter and co-substrate for vital enzymatic reactions, it has become a cornerstone for researchers examining sirtuin (SIRT) activation, PARP-mediated DNA repair, and mitochondrial bioenergetics.
At 4 Amino Labs, we provide this delicate dinucleotide in a stabilized, high-purity format to ensure experimental reproducibility. By maintaining rigorous measurement standards, we provide the consistency required for longitudinal data integrity.
Scientific Literature Reference: The critical decline of NAD+ during cellular senescence and its obligate role as a substrate for longevity-associated enzymes is thoroughly established. See: Verdin, E. (2015). “NAD⁺ in aging, metabolism, and neurodegeneration.” Science, 350(6265), 1208-1213.
Analytical Composition & Purity Standards
- Chemical Formula: C21H27N7O14P2
- Physical State: White Lyophilized Powder / Stabilized Solution
Our NAD+ undergoes a multifaceted verification process. Each batch is subjected to independent High-Performance Liquid Chromatography (HPLC) to ensure a purity threshold of ≥ 99%. This analytical rigor ensures the absence of degraded breakdown products, providing a highly stable baseline for your in-vitro models.
Investigational Pathways
NAD+ typically focus on the following biochemical mechanisms:
- Sirtuin Activation: Evaluating the compound’s role as the obligate co-substrate for SIRT1-7 deacetylases, regulating metabolic gene expression.
- DNA Repair (PARP): Observing the consumption of NAD+ by poly(ADP-ribose) polymerases in response to induced genomic damage.
- Redox Cycling: Mapping the continuous NAD+/NADH ratio during glycolysis and the citric acid cycle in isolated cellular assays.
- Cellular Senescence: Investigating the agent’s capacity to rescue mitochondrial function in aged or oxidatively stressed in vitro models.
Laboratory Handling & Stability Protocol
To maintain the molecular integrity of NAD+, the following storage parameters are recommended:
- Thermal Regulation: Extremely heat sensitive. Store at -20°C for long-term preservation. Thaw cautiously only when preparing working aliquots.
- Photostability: Protect from direct UV exposure; storage in an opaque container is strictly advised.
- Hygroscopic Prevention: Highly hygroscopic; ensure the seal is hermetic in a desiccated environment.
- Contamination Control: Use sterilized instruments and work within a laminar-flow hood, when possible, to maintain sample sterility.
Compliance & Safety Disclaimer
This substance is provided exclusively for in-vitro laboratory research and pre-clinical developmental testing. 4 Amino Lab does not condone or authorize the use of this product in any clinical setting or for personal consumption. Misuse of laboratory chemicals carries significant health risks. By purchasing, the researcher acknowledges the inherent risks and confirms they possess the necessary equipment and expertise to handle these materials safely.