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Tamoxifen

Tamoxifen

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Size

20mg/mL solution (600mg/30mL)

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Tamoxifen
Clinical data
Other names TMX; ICI-46474
AHFS/Drugs.com Monograph
MedlinePlus a682414
License data
Pregnancy
category
Routes of
administration
By mouth
Drug class Selective estrogen receptor modulator
ATC code
Pharmacokinetic data
Bioavailability ~100%[5][6]
Protein binding >99% (albumin)[5][7]
Metabolism Liver (CYP3A4, CYP2C9, CYP2D6)[5][12][8]
Metabolites  N-Desmethyltamoxifen[8][9]
 Endoxifen (4-hydroxy-N-desmethyltamoxifen)[8][9]
 Afimoxifene (4-hydroxytamoxifen)[8][9]
 N,N-Didesmethyltamoxifen[8]
 Norendoxifen (4-hydroxy-N,N-didesmethyltamoxifen)[8]
• Others, conjugates[8][10][11]
Elimination half-life 5–7 days[5][8]
Excretion Feces: 65%
Urine: 9%
Identifiers
CAS Number
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
PDB ligand
CompTox Dashboard (EPA)
ECHA InfoCard 100.031.004 Edit this at Wikidata
Chemical and physical data
Formula C26H29NO
Molar mass 371.524 g·mol−1
3D model (JSmol)
  (verify)

**The information provided is intended solely for educational purposes and should not be considered a replacement for professional medical advice. Additionally, it is important to note that research chemicals are intended solely for laboratory study by professional researchers and are not intended for human consumption.**

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