Dutasteride
Dutasteride
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| Clinical data | |
|---|---|
| Other names | GG-745; GI-198745; GI-198745X; N-[2,5-Bis(trifluoromethyl)phenyl]-3-oxo-4-aza-5α-androst-1-ene-17β-carboxamide |
| AHFS/Drugs.com | Monograph |
| MedlinePlus | a603001 |
| License data |
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| Pregnancy category |
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| Routes of administration |
By mouth |
| Drug class | 5α-Reductase inhibitor |
| ATC code | |
| Pharmacokinetic data | |
| Bioavailability | 60%[1] |
| Protein binding | 99%[1] |
| Metabolism | Liver (CYP3A4)[1] |
| Metabolites | • 4'-Hydroxydutasteride[1] • 6'-Hydroxydutasteride[1] • 1,2-Dihydrodutasteride[1] (All three active)[1] |
| Elimination half-life | 4–5 weeks[2][3] |
| Excretion |
Feces: 40% (metabolites)[1] Urine: 5% (unchanged)[1] |
| Identifiers | |
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| CAS Number | |
| PubChem CID | |
| IUPHAR/BPS | |
| DrugBank | |
| ChemSpider | |
| UNII | |
| KEGG | |
| ChEBI | |
| ChEMBL | |
| CompTox Dashboard (EPA) | |
| ECHA InfoCard | 100.166.372 |
| Chemical and physical data | |
| Formula | C27H30F6N2O2 |
| Molar mass | 528.539 g·mol−1 |
| 3D model (JSmol) | |
**The information provided is intended solely for educational purposes and should not be considered a replacement for professional medical advice. Additionally, it is important to note that research chemicals are intended solely for laboratory study by professional researchers and are not intended for human consumption.**
