Mechanism of Action

SLU-PP-332 is a potent estrogen receptor-related (ERR) agonist that mimics the health benefits of exercise. Its mechanism of action is based on the following:

• ERR Activation: SLU-PP-332 acts as a non-selective agonist for ERRα, ERRβ, and ERRγ, with EC50 values of 98 nM, 230 nM, and 430 nM, respectively.

• Metabolic Enhancement: It increases energy expenditure and fatty acid oxidation, similar to the effects of exercise.

• Mitochondrial Function: SLU-PP-332 enhances mitochondrial function and cellular respiration.

• Muscle Fiber Composition: It increases type IIa oxidized skeletal muscle fibers.

Benefits

SLU-PP-332 offers a range of potential benefits, including:

• Reduced fat mass accumulation

• Improved insulin sensitivity

• Enhanced exercise tolerance

• Potential treatment for obesity and metabolic syndrome

• Possible applications in treating type 2 diabetes, heart failure, kidney disease, and cognitive dysfunction

Side Effects

While specific side effects of SLU-PP-332 are not extensively documented, potential concerns may include:

• Unknown long-term effects

• Possible hormonal imbalances due to ERR activation

• Potential cardiovascular effects

Usage Guidelines

As SLU-PP-332 is still in preclinical stages, there are no established usage guidelines for humans. However, based on research:

• Administration in mouse models has shown promising results

• Improved versions are being developed for potential clinical trials

Current Research Status

SLU-PP-332 is currently in preclinical phases of research:

• Tested successfully in mouse models of obesity and metabolic syndrome

• Showing potential as a therapeutic for metabolic diseases

• Further optimization is ongoing for possible future clinical trials

The information provided in this guide is intended solely for educational purposes and should not be considered a replacement for professional medical advice. It's important to note that SLU-PP-332 is a research chemical intended only for laboratory study by professional researchers and is not intended for human consumption.

Solid Anecdotal Report I've Found Below:

The one in which I chronical my slu-pp-332 journey. : r/SLUPP332 (reddit.com)

PDF Download from Journal of Renal Endocrinology regarding SLU PP 332